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Protein Ontology report - Bcl-2-like protein 11 (human)
PR:O43521 - http://purl.obolibrary.org/obo/PR_O43521
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:O43521   
  PRO nameBcl-2-like protein 11 (human) 
  Synonyms
PRO-Short-label: EXACT:hBCL2L11
Gene-based: RELATED:BCL2L11 | BIM
Other: EXACT:Bcl2-interacting mediator of cell death (human) | Bcl2-L-11 (human)
  Definition"A Bcl-2-like protein 11 that is encoded in the genome of human." [PRO:WCB, UniProtKB:O43521
  PRO Categoryorganism-gene 
  ParentPR:000002187 Bcl-2-like protein 11
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:994 BCL2L11 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 20                                        
         Modification0                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:O43521
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:O43521

Bcl-2-like protein 11 (human)

hBCL2L11


"A Bcl-2-like protein 11 that is encoded in the genome of human." [PRO:WCB, UniProtKB:O43521]


organism-sequence



PR:O43521-1

Bcl-2-like protein 11 isoform BimEL (human)

hBCL2L11/iso:BimEL


"A Bcl-2-like protein 11 isoform 1 that is encoded in the genome of human." [PRO:JAN]


organism-modification



PR:000025727

Bcl-2-like protein 11 isoform 1 phosphorylated 1 (human)

hBCL2L11/iso:1/Phos:1


"A Bcl-2-like protein 11 isoform 1 phosphorylated 1 in human. UniProtKB:O43521-1, Ser-87, MOD:00046." [PMID:16282323, PRO:JAN]

Yes

organism-sequence



PR:O43521-10

Bcl-2-like protein 11 isoform Bim-beta1 (human)

hBCL2L11/iso:Bim-beta1


"A Bcl-2-like protein 11 isoform 10 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:O43521-11

Bcl-2-like protein 11 isoform Bim-beta2 (human)

hBCL2L11/iso:Bim-beta2


"A Bcl-2-like protein 11 isoform 11 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:O43521-12

Bcl-2-like protein 11 isoform Bim-beta3 (human)

hBCL2L11/iso:Bim-beta3


"A Bcl-2-like protein 11 isoform 12 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:O43521-13

Bcl-2-like protein 11 isoform Bim-beta4 (human)

hBCL2L11/iso:Bim-beta4


"A Bcl-2-like protein 11 isoform 13 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:O43521-14

Bcl-2-like protein 11 isoform Bim-beta5 (human)

hBCL2L11/iso:Bim-beta5


"A Bcl-2-like protein 11 isoform 14 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:O43521-15

Bcl-2-like protein 11 isoform Bim-beta6 (human)

hBCL2L11/iso:Bim-beta6


"A Bcl-2-like protein 11 isoform 15 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:O43521-16

Bcl-2-like protein 11 isoform Bim-beta7 (human)

hBCL2L11/iso:Bim-beta7


"A Bcl-2-like protein 11 isoform 16 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:O43521-17

Bcl-2-like protein 11 isoform Bim-gamma (human)

hBCL2L11/iso:Bim-gamma


"A Bcl-2-like protein 11 isoform 17 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:O43521-18

Bcl-2-like protein 11 isoform BimABC (human)

hBCL2L11/iso:BimABC


"A Bcl-2-like protein 11 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43521-18." [PRO:DNx, UniProtKB:O43521]


organism-sequence



PR:O43521-19

Bcl-2-like protein 11 isoform BimAC (human)

hBCL2L11/iso:BimAC


"A Bcl-2-like protein 11 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43521-19." [PRO:DNx, UniProtKB:O43521]


organism-sequence



PR:O43521-2

Bcl-2-like protein 11 isoform BimL (human)

hBCL2L11/iso:BimL


"A Bcl-2-like protein 11 isoform 2 that is encoded in the genome of human." [PRO:JAN]

Yes

organism-modification



PR:000036641

Bcl-2-like protein 11 isoform 2 phosphorylated 1 (human)

hBCL2L11/iso:2/Phos:1


"A Bcl-2-like protein 11 isoform 2 phosphorylated 1 in human. UniProtKB:O43521-2, Ser-44/Ser-58, MOD:00046|Thr-56, MOD:00047." [PMID:12591950, PRO:JAN]

Yes

organism-modification



PR:000044746

Bcl-2-like protein 11 isoform 2 unmodified form (human)

hBCL2L11/iso:2/UnMod


"A Bcl-2-like protein 11 isoform 2 unmodified form in human." [PRO:DNx]

Yes

organism-sequence



PR:O43521-20

Bcl-2-like protein 11 isoform BimA (human)

hBCL2L11/iso:BimA


"A Bcl-2-like protein 11 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43521-20." [PRO:DNx, UniProtKB:O43521]


organism-sequence



PR:O43521-3

Bcl-2-like protein 11 isoform BimS (human)

hBCL2L11/iso:BimS


"A Bcl-2-like protein 11 isoform 3 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:O43521-4

Bcl-2-like protein 11 isoform Bim-alpha1 (human)

hBCL2L11/iso:Bim-alpha1


"A Bcl-2-like protein 11 isoform 4 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:O43521-5

Bcl-2-like protein 11 isoform Bim-alpha2 (human)

hBCL2L11/iso:Bim-alpha2


"A Bcl-2-like protein 11 isoform 5 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:O43521-6

Bcl-2-like protein 11 isoform Bim-alpha3 (human)

hBCL2L11/iso:Bim-alpha3


"A Bcl-2-like protein 11 isoform 6 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:O43521-7

Bcl-2-like protein 11 isoform Bim-alpha4 (human)

hBCL2L11/iso:Bim-alpha4


"A Bcl-2-like protein 11 isoform 7 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:O43521-8

Bcl-2-like protein 11 isoform Bim-alpha5 (human)

hBCL2L11/iso:Bim-alpha5


"A Bcl-2-like protein 11 isoform 8 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:O43521-9

Bcl-2-like protein 11 isoform Bim-alpha6 (human)

hBCL2L11/iso:Bim-alpha6


"A Bcl-2-like protein 11 isoform 9 that is encoded in the genome of human." [PRO:JAN]


organism-modification



PR:000046477

Bcl-2-like protein 11 phosphorylated form (human)

hBCL2L11/PhosRes+


"A Bcl-2-like protein 11 (human) that includes at least one phosphorylated residue. UniProtKB:O43521, MOD:00696." [PRO:DNx, Reactome:R-HSA-140525, Reactome:R-HSA-3145027]


organism-modification



PR:000025727

Bcl-2-like protein 11 isoform 1 phosphorylated 1 (human)

hBCL2L11/iso:1/Phos:1


"A Bcl-2-like protein 11 isoform 1 phosphorylated 1 in human. UniProtKB:O43521-1, Ser-87, MOD:00046." [PMID:16282323, PRO:JAN]

Yes

organism-modification



PR:000036641

Bcl-2-like protein 11 isoform 2 phosphorylated 1 (human)

hBCL2L11/iso:2/Phos:1


"A Bcl-2-like protein 11 isoform 2 phosphorylated 1 in human. UniProtKB:O43521-2, Ser-44/Ser-58, MOD:00046|Thr-56, MOD:00047." [PMID:12591950, PRO:JAN]

Yes

organism-modification



PR:000046476

Bcl-2-like protein 11 phosphorylated 1 (human)

hBCL2L11/Phos:1


"A Bcl-2-like protein 11 (human) that has been phosphorylated on the residue at the position equivalent to Ser-69 of the amino acid sequence represented by UniProtKB:O43521. UniProtKB:O43521, Ser-69, MOD:00046." [iPTMnet:O43521, PMID:14555991, PRO:DAN, Reactome:R-HSA-2976671]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000025727 hBCL2L11/iso:1/Phos:1
UniProtKB:O43521-1, Ser-87, MOD:00046
acts_upstream_of_or_withinGO:0043066 negative regulation of apoptotic process PMID:16282323
enablesGO:0005515 protein binding with PR:P31946 hYWHAB PMID:16282323
PR:000036641 hBCL2L11/iso:2/Phos:1
UniProtKB:O43521-2, Ser-44/Ser-58, MOD:00046|Thr-56, MOD:00047
acts_upstream_of_or_withinGO:0012501 programmed cell death PMID:12591950
enablesdecreased GO:0005515 protein binding with PR:Q96QB1 ARHGAP7 PMID:12591950
PR:000044746 hBCL2L11/iso:2/UnMod enablesGO:0005515 protein binding with PR:Q96QB1 ARHGAP7 PMID:12591950
PR:O43521-2 hBCL2L11/iso:BimL enablesGO:0005515 protein binding with PR:Q07812 BAX PMID:14764673