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Protein Ontology report - cubilin (human)
PR:O60494 - http://purl.obolibrary.org/obo/PR_O60494
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:O60494   
  PRO namecubilin (human) 
  Synonyms
PRO-Short-label: EXACT:hCUBN
Gene-based: RELATED:CUBN | IFCR
Other: EXACT:460 kDa receptor (human) | intestinal intrinsic factor receptor (human) | intrinsic factor-cobalamin receptor (human) | intrinsic factor-vitamin B12 receptor (human)
  Definition"A cubilin that is encoded in the genome of human." [PRO:DNx, UniProtKB:O60494
  PRO Categoryorganism-gene 
  ParentPR:000006043 cubilin
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:2548 CUBN (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification0                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:O60494
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:O60494

cubilin (human)

hCUBN


"A cubilin that is encoded in the genome of human." [PRO:DNx, UniProtKB:O60494]


organism-modification



PR:000050782

cubilin N-glycosylated 1 (human)

hCUBN/NGlyco:1


"A cubilin (human) that has been N-glycosylated at the residue equivalent to Asn-2085 of the amino acid sequence represented by UniProtKB:O60494-1, in which the glycan composition is represented by GlyTouCan:G59334JE. Example: UniProtKB:O60494-1, Asn-2085, MOD:00160~GNO:G59334JE." [GlyGen:O60494-1, PMID:26791533, PRO:DNx]


organism-modification



PR:000050783

cubilin N-glycosylated 2 (human)

hCUBN/NGlyco:2


"A cubilin (human) that has been N-glycosylated at the residue equivalent to Asn-2531 of the amino acid sequence represented by UniProtKB:O60494-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:O60494-1, Asn-2531, MOD:00160~GNO:G00912UN." [GlyGen:O60494-1, PMID:29671580, PRO:DNx]


organism-modification



PR:000050784

cubilin O-glycosylated 1 (human)

hCUBN/OGlyco:1


"A cubilin (human) that has been O-glycosylated at the residue equivalent to Ser-2904 of the amino acid sequence represented by UniProtKB:O60494-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:O60494-1, Ser-2904, MOD:00002~GNO:G43417UB." [GlyGen:O60494-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000050785

cubilin O-glycosylated 2 (human)

hCUBN/OGlyco:2


"A cubilin (human) that has been O-glycosylated at the residue equivalent to Ser-3591 of the amino acid sequence represented by UniProtKB:O60494-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:O60494-1, Ser-3591, MOD:00002~GNO:G43417UB." [GlyGen:O60494-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000050786

cubilin O-glycosylated 3 (human)

hCUBN/OGlyco:3


"A cubilin (human) that has been O-glycosylated at the residue equivalent to Ser-688 of the amino acid sequence represented by UniProtKB:O60494-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:O60494-1, Ser-688, MOD:00002~GNO:G29068FM." [GlyGen:O60494-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000050787

cubilin O-glycosylated 4 (human)

hCUBN/OGlyco:4


"A cubilin (human) that has been O-glycosylated at the residue equivalent to Thr-1972 of the amino acid sequence represented by UniProtKB:O60494-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:O60494-1, Thr-1972, MOD:00005~GNO:G29068FM." [GlyGen:O60494-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000050788

cubilin O-glycosylated 5 (human)

hCUBN/OGlyco:5


"A cubilin (human) that has been O-glycosylated at the residue equivalent to Thr-1972 of the amino acid sequence represented by UniProtKB:O60494-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:O60494-1, Thr-1972, MOD:00005~GNO:G43417UB." [GlyGen:O60494-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000066403

cubilin, mature form (human)

hCUBN/mature


"A cubilin (human) that has had the signal peptide and propeptide removed. UniProtKB:O60494, 36-3623." [PRO:DNx, Reactome:R-HSA-264843, Reactome:R-HSA-350088, Reactome:R-HSA-350162]


organism-modification



PR:000066418

cubilin sequence variant P1297L, mature form (human)

hCUBN/var:P1297L/mature


"A cubilin (human) that has a Leu residue at the position equivalent to Pro-1297 of the amino acid sequence represented by UniProtKB:O60494 and that has had the signal peptide and propeptide removed. UniProtKB:O60494, 36-3623, Pro-1297, CHEBI:30006." [PRO:DNx, Reactome:R-HSA-3296479]