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Protein Ontology report - nuclear factor of activated T-cells, cytoplasmic 1 (human)
PR:O95644 - http://purl.obolibrary.org/obo/PR_O95644
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:O95644   
  PRO namenuclear factor of activated T-cells, cytoplasmic 1 (human) 
  Synonyms
PRO-Short-label: EXACT:hNFATC1
Gene-based: RELATED:NFAT2 | NFATC | NFATC1
Other: EXACT:NF-ATc (human) | NF-ATc1 (human) | NFAT transcription complex cytosolic component (human) | NFATc1 (human)
  Definition"A nuclear factor of activated T-cells, cytoplasmic 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:O95644] 
  PRO Categoryorganism-gene 
  ParentPR:000003113 nuclear factor of activated T-cells, cytoplasmic 1
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:7775 NFATC1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 10                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:O95644
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:O95644
nuclear factor of activated T-cells, cytoplasmic 1 (human)
hNFATC1
"A nuclear factor of activated T-cells, cytoplasmic 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:O95644]

organism-sequence


PR:O95644-1
nuclear factor of activated T-cells, cytoplasmic 1 isoform C-alpha (human)
hNFATC1/iso:C-alpha
"A nuclear factor of activated T-cells, cytoplasmic 1 isoform 1 that is encoded in the genome of human." [PRO:JAN]
Yes
organism-modification


PR:000036638
nuclear factor of activated T-cells, cytoplasmic 1 isoform 1 phosphorylated 1 (human)
hNFATC1/iso:1/Phos:1
"A nuclear factor of activated T-cells, cytoplasmic 1 isoform 1 phosphorylated 1 in human. UniProtKB:O95644-1, Ser-117/Ser-172, MOD:00046." [PMID:10866678, PRO:JAN]
Yes
organism-sequence


PR:O95644-10
nuclear factor of activated T-cells, cytoplasmic 1 isoform IA-deltaIX (human)
hNFATC1/iso:IA-deltaIX
"A nuclear factor of activated T-cells, cytoplasmic 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95644-10." [PRO:DNx, UniProtKB:O95644]

organism-sequence


PR:O95644-11
nuclear factor of activated T-cells, cytoplasmic 1 isoform IB-deltaIX (human)
hNFATC1/iso:IB-deltaIX
"A nuclear factor of activated T-cells, cytoplasmic 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95644-11." [PRO:DNx, UniProtKB:O95644]

organism-sequence


PR:O95644-17
nuclear factor of activated T-cells, cytoplasmic 1 isoform h10 (human)
hNFATC1/iso:h10
"A nuclear factor of activated T-cells, cytoplasmic 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95644-17." [PRO:DNx, UniProtKB:O95644]

organism-sequence


PR:O95644-2
nuclear factor of activated T-cells, cytoplasmic 1 isoform A-alpha (human)
hNFATC1/iso:A-alpha
"A nuclear factor of activated T-cells, cytoplasmic 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95644-2." [PRO:DNx, UniProtKB:O95644]

organism-sequence


PR:O95644-3
nuclear factor of activated T-cells, cytoplasmic 1 isoform A-beta (human)
hNFATC1/iso:A-beta
"A nuclear factor of activated T-cells, cytoplasmic 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95644-3." [PRO:DNx, UniProtKB:O95644]

organism-sequence


PR:O95644-4
nuclear factor of activated T-cells, cytoplasmic 1 isoform B-alpha (human)
hNFATC1/iso:B-alpha
"A nuclear factor of activated T-cells, cytoplasmic 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95644-4." [PRO:DNx, UniProtKB:O95644]

organism-sequence


PR:O95644-5
nuclear factor of activated T-cells, cytoplasmic 1 isoform B-beta (human)
hNFATC1/iso:B-beta
"A nuclear factor of activated T-cells, cytoplasmic 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95644-5." [PRO:DNx, UniProtKB:O95644]

organism-sequence


PR:O95644-6
nuclear factor of activated T-cells, cytoplasmic 1 isoform C-beta (human)
hNFATC1/iso:C-beta
"A nuclear factor of activated T-cells, cytoplasmic 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95644-6." [PRO:DNx, UniProtKB:O95644]

organism-sequence


PR:O95644-8
nuclear factor of activated T-cells, cytoplasmic 1 isoform A-alpha' (human)
hNFATC1/iso:A-alpha'
"A nuclear factor of activated T-cells, cytoplasmic 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95644-8." [PRO:DNx, UniProtKB:O95644]

organism-modification


PR:000048588
nuclear factor of activated T-cells, cytoplasmic 1 phosphorylated 2 (human)
hNFATC1/Phos:2
"A nuclear factor of activated T-cells, cytoplasmic 1 (human) that has been post-translationally modified to include phosphoserine at positions 175, 176, 178, 179, 181, 233, 237, 241, 257, 278, 286 and 290 of the amino acid sequence represented by UniProtKB:O95644. UniProtKB:O95644, Ser-175/Ser-176/Ser-178/Ser-179/Ser-181/Ser-233/Ser-237/Ser-241/Ser-257/Ser-278/Ser-286/Ser-290, MOD:00046." [PRO:DNx, Reactome:R-HSA-2025953]

organism-modification


PR:000048589
nuclear factor of activated T-cells, cytoplasmic 1 phosphorylated 3 (human)
hNFATC1/Phos:3
"A nuclear factor of activated T-cells, cytoplasmic 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-257 of the amino acid sequence represented by UniProtKB:O95644. UniProtKB:O95644, Ser-257, MOD:00046." [PRO:DNx, Reactome:R-HSA-2025935, Reactome:R-HSA-2685618]

organism-modification


PR:000069331
nuclear factor of activated T-cells, cytoplasmic 1 cysteinylated 1 (human)
hNFATC1/Cyst:1
"A nuclear factor of activated T-cells, cytoplasmic 1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-125 of the amino acid sequence represented by UniProtKB:O95644-1. Example: UniProtKB:O95644-1, Cys-125, MOD:00765." [IEDB_epitope:1050875, PRO:DNx]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036638 hNFATC1/iso:1/Phos:1
UniProtKB:O95644-1, Ser-117/Ser-172, MOD:00046		 enablesGO:0005515 protein binding with PR:O14980 chromosome region maintenance 1 protein homolog (human) PMID:10866678
located_inGO:0005737 cytoplasm PMID:10866678
PR:O95644-1 hNFATC1/iso:C-alpha enablesincreased GO:0005515 protein binding with PR:P45983 c-Jun N-terminal kinase 1 (human) PMID:10866678
increased GO:0005515 protein binding with PR:O14980 chromosome region maintenance 1 protein homolog (human) PMID:10866678
located_inGO:0005634 nucleus PMID:10866678