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Protein Ontology report - tyrosine-protein kinase ABL1 (human)
PR:P00519 - http://purl.obolibrary.org/obo/PR_P00519
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P00519   
  PRO nametyrosine-protein kinase ABL1 (human) 
  Synonyms
PRO-Short-label: EXACT:hABL1
Gene-based: RELATED:ABL | ABL1 | JTK7
Other: EXACT:Abelson murine leukemia viral oncogene homolog 1 (human) | Abelson tyrosine-protein kinase 1 (human) | proto-oncogene c-Abl (human)
  Definition"A tyrosine-protein kinase ABL1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P00519
  PRO Categoryorganism-gene 
  ParentPR:000003582 tyrosine-protein kinase ABL1
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:76 ABL1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P00519
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:P00519

tyrosine-protein kinase ABL1 (human)

hABL1


"A tyrosine-protein kinase ABL1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P00519]


organism-sequence



PR:P00519-1

tyrosine-protein kinase ABL1 isoform 1 (human)

hABL1/iso:1


"A tyrosine-protein kinase ABL1 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:P00519-2

tyrosine-protein kinase ABL1 isoform 2 (human)

hABL1/iso:2


"A tyrosine-protein kinase ABL1 isoform 2 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000028614

tyrosine-protein kinase ABL1 isoform 2 acetylated 1 (human)

hABL1/iso:2/Ac:1


"A tyrosine-protein kinase ABL1 isoform 2 acetylated 1 in human. UniProtKB:P00519-2, Lys-730, MOD:00064." [KAT:P00519-2, PMID:16648821, PRO:PD]


organism-modification



PR:000044506

tyrosine-protein kinase ABL1 phosphorylated 1 (human)

hABL1/Phos:1


"A tyrosine-protein kinase ABL1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-735 of the amino acid sequence represented by UniProtKB:P00519-1. Example: UniProtKB:P00519-1, Thr-735, MOD:00047." [PMID:15696159, PMID:16888623, PRO:CNA]

Yes

organism-modification



PR:000046226

tyrosine-protein kinase ABL1 phosphorylated 2 (human)

hABL1/Phos:2


"A tyrosine-protein kinase ABL1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-446 of the amino acid sequence represented by UniProtKB:P00519. UniProtKB:P00519, Ser-446, MOD:00046." [PRO:DAN, Reactome:R-HSA-5686576]


organism-modification



PR:000075644

tyrosine-protein kinase ABL1 methylated 1 (human)

hABL1/Me:1


"A tyrosine-protein kinase ABL1 (human) that has been methylated on the residue at the position equivalent to Cys-1100 of the amino acid sequence represented by UniProtKB:P00519-1. Example: UniProtKB:P00519-1, Cys-1100, MOD:00660." [IEDB_epitope:1041130, PRO:DNx]


organism-modification



PR:000077670

tyrosine-protein kinase ABL1 deaminated 1 (human)

hABL1/Deam:1


"A tyrosine-protein kinase ABL1 (human) that has been deaminated on the residue at the position equivalent to Gln-1112 of the amino acid sequence represented by UniProtKB:P00519-1. Example: UniProtKB:P00519-1, Gln-1112, MOD:00685." [IEDB_epitope:1365553, PRO:DNx]


organism-modification



PR:000085814

tyrosine-protein kinase ABL1 phosphorylated 3 (human)

hABL1/Phos:3


"A tyrosine-protein kinase ABL1 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-393 of the amino acid sequence represented by UniProtKB:P00519-1. Example: UniProtKB:P00519-1, Tyr-393, MOD:00048." [PRO:DNx, Reactome:R-HSA-9865161]


organism-modification



PR:000086246

tyrosine-protein kinase ABL1 phosphorylated 4 (human)

hABL1/Phos:4


"A tyrosine-protein kinase ABL1 (human) that has been phosphorylated on the residues at the positions equivalent to Tyr-226 and Tyr-393 of the amino acid sequence represented by UniProtKB:P00519-1. Example: UniProtKB:P00519-1, Tyr-226/Tyr-393, MOD:00048." [PRO:DNx, Reactome:R-HSA-8942610, Reactome:R-HSA-8985251]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000044506 hABL1/Phos:1
Example: UniProtKB:P00519-1, Thr-735, MOD:00047
enablesGO:0071889 14-3-3 protein binding with PR:000044507 fam:14-3-3 (human) PMID:15696159
GO:0071889 14-3-3 protein binding with PR:P63104 hYWHAZ PMID:15696159
located_inGO:0005737 cytoplasm PMID:15696159