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Protein Ontology report - transcription factor AP-2-alpha (human)
PR:P05549 - http://purl.obolibrary.org/obo/PR_P05549
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:P05549   
  PRO nametranscription factor AP-2-alpha (human) 
  Synonyms
PRO-Short-label: EXACT:hTFAP2A
Gene-based: RELATED:AP2TF | TFAP2 | TFAP2A
Other: EXACT:activating enhancer-binding protein 2-alpha (human) | activator protein 2 (human) | AP-2 (human) | AP-2 transcription factor (human) | AP2-alpha (human)
  Definition"A transcription factor AP-2-alpha that is encoded in the genome of human." [PRO:DNx, UniProtKB:P05549] 
  PRO Categoryorganism-gene 
  ParentPR:000016263 transcription factor AP-2-alpha
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:11742 TFAP2A (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P05549
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:P05549
transcription factor AP-2-alpha (human)
hTFAP2A
"A transcription factor AP-2-alpha that is encoded in the genome of human." [PRO:DNx, UniProtKB:P05549]

organism-sequence


PR:P05549-1
transcription factor AP-2-alpha isoform 1 (human)
hTFAP2A/iso:1
"A transcription factor AP-2-alpha isoform 1 that is encoded in the genome of human." [PRO:AAA, UniProtKB:P05549-1]
Yes
organism-modification


PR:000064675
transcription factor AP-2-alpha isoform 1 sumoylated 1 (human)
hTFAP2A/iso:1/Sumo:1
"A transcription factor AP-2-alpha isoform 1 (human) that has been sumoylated on the residue at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:P05549-1. UniProtKB:P05549-1, Lys-10, MOD:01149." [PRO:DNx, Reactome:R-HSA-3234080]

organism-sequence


PR:P05549-2
transcription factor AP-2-alpha isoform 4 (human)
hTFAP2A/iso:4
"A transcription factor AP-2-alpha isoform 4 that is encoded in the genome of human." [PRO:AAA, UniProtKB:P05549-2]
Yes
organism-sequence


PR:P05549-5
transcription factor AP-2-alpha isoform 2 (human)
hTFAP2A/iso:2
"A transcription factor AP-2-alpha isoform 5 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:P05549-6
transcription factor AP-2-alpha isoform h5 (human)
hTFAP2A/iso:h5
"A transcription factor AP-2-alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05549-6." [PRO:DNx, UniProtKB:P05549]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P05549-1 hTFAP2A/iso:1 acts_upstream_of_or_withinGO:0045944 positive regulation of transcription by RNA polymerase II PMID:8321221
PR:P05549-2 hTFAP2A/iso:4 acts_upstream_of_or_withinGO:0000122 negative regulation of transcription by RNA polymerase II PMID:8321221