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Protein Ontology report - platelet-derived growth factor receptor beta (human)
PR:P09619 - http://purl.obolibrary.org/obo/PR_P09619
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P09619   
  PRO nameplatelet-derived growth factor receptor beta (human) 
  Synonyms
PRO-Short-label: EXACT:hPDGFRB
Gene-based: RELATED:PDGFR | PDGFR1 | PDGFRB
Other: EXACT:beta platelet-derived growth factor receptor (human) | beta-type platelet-derived growth factor receptor (human) | CD140 antigen-like family member B (human) | CD140b (human) | PDGF-R-beta (human) | PDGFR-1 (human) | PDGFR-beta (human) | platelet-derived growth factor receptor 1 (human)
  Definition"A beta-type platelet-derived growth factor receptor that is encoded in the genome of human." [PRO:WCB, UniProtKB:P09619] 
  PRO Categoryorganism-gene 
  ParentPR:000002035 beta-type platelet-derived growth factor receptor
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:8804 PDGFRB (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P09619
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:P09619 platelet-derived growth factor receptor beta (human)
hPDGFRB

organism-sequence


PR:P09619-1 platelet-derived growth factor receptor beta isoform 1 (human)
hPDGFRB/iso:1

organism-sequence


PR:P09619-2 platelet-derived growth factor receptor beta isoform h2 (human)
hPDGFRB/iso:h2

organism-modification


PR:000048725 platelet-derived growth factor receptor beta, signal peptide removed form (human)
hPDGFRB/SigPep-

organism-modification


PR:000048726 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 1 (human)
hPDGFRB/SigPep-/Phos:1

organism-modification


PR:000049846 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 2 (human)
hPDGFRB/SigPep-/Phos:2
Yes
organism-modification


PR:000049847 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 3 (human)
hPDGFRB/SigPep-/Phos:3
Yes
organism-modification


PR:000049848 platelet-derived growth factor receptor beta, signal peptide removed unphosphorylated 2 (human)
hPDGFRB/SigPep-/UnPhos:2
Yes
organism-modification


PR:000064602 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 4 (human)
hPDGFRB/SigPep-/Phos:4

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
increased GO:0018108 peptidyl-tyrosine phosphorylationPR:000049846 hPDGFRB/SigPep-/Phos:2 PMID:1653029; PMID:9642269
GO:0038083 peptidyl-tyrosine autophosphorylationPR:000049848 hPDGFRB/SigPep-/UnPhos:2 PMID:9642269
decreased GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transductionPR:000049847 hPDGFRB/SigPep-/Phos:3 PMID:15271984

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0004713 protein tyrosine kinase activityPR:000049846 hPDGFRB/SigPep-/Phos:2 PMID:15994317; PMID:9642269
PR:000049847 hPDGFRB/SigPep-/Phos:3 PMID:15271984
GO:0005515 protein bindingPR:000049846 hPDGFRB/SigPep-/Phos:2 PMID:1653029
PR:000049847 hPDGFRB/SigPep-/Phos:3 PMID:15271984