back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - bone morphogenetic protein 4 (human)
PR:P12644 - http://purl.obolibrary.org/obo/PR_P12644
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:P12644   
  PRO namebone morphogenetic protein 4 (human) 
  Synonyms
PRO-Short-label: EXACT:hBMP4
Gene-based: RELATED:BMP2B | BMP4 | DVR4
Other: EXACT:BMP-2B (human) | BMP-4 (human) | bone morphogenetic protein 2B (human)
  Definition"A bone morphogenetic protein 4 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P12644] 
  PRO Categoryorganism-gene 
  ParentPR:000000165 bone morphogenetic protein 4
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:1071 BMP4 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
UniProtKB:P12644
Back to top
Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:P12644
bone morphogenetic protein 4 (human)
hBMP4
"A bone morphogenetic protein 4 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P12644]

organism-sequence


PR:P12644-1
bone morphogenetic protein 4 isoform 1 (human)
hBMP4/iso:1
"A bone morphogenetic protein 4 isoform 1 that is encoded in the genome of human." [PRO:CNA]
Yes
organism-modification


PR:000036511
bone morphogenetic protein 4 isoform 1, mature form (human)
hBMP4/iso:1/mature
"A bone morphogenetic protein 4 isoform 1, mature form in human. UniProtKB:P12644-1, 293-408." [PMID:11401399, PMID:12141440, PMID:12805376, PMID:14660436, PMID:14749725, PMID:9804553, PRO:CNA]
Yes
organism-modification


PR:000046492
bone morphogenetic protein 4, signal peptide removed form (human)
hBMP4/SigPep-
"A bone morphogenetic protein 4 (human) that has had the signal peptide removed. UniProtKB:P12644, 20-408." [PRO:DNx, Reactome:R-HSA-2396280]

organism-modification


PR:000072771
bone morphogenetic protein 4, mature form (human)
hBMP4/mature
"A bone morphogenetic protein 4 (human) that has had the signal peptide and propeptide removed. UniProtKB:P12644, 293-408." [PRO:DNx, Reactome:R-HSA-8858573, Reactome:R-HSA-8956775]

organism-modification


PR:000036511
bone morphogenetic protein 4 isoform 1, mature form (human)
hBMP4/iso:1/mature
"A bone morphogenetic protein 4 isoform 1, mature form in human. UniProtKB:P12644-1, 293-408." [PMID:11401399, PMID:12141440, PMID:12805376, PMID:14660436, PMID:14749725, PMID:9804553, PRO:CNA]
Yes
organism-modification


PR:000072824
bone morphogenetic protein 4, mature phosphorylated form (human)
hBMP4/mature/PhosRes+
"A bone morphogenetic protein 4 (human) that has had the signal peptide and propeptide removed, and that includes at least one phosphorylated residue. UniProtKB:P12644, 293-408, MOD:00696." [PRO:DNx, Reactome:R-HSA-8956944]

organism-modification


PR:000072771
bone morphogenetic protein 4, mature form (human)
hBMP4/mature
"A bone morphogenetic protein 4 (human) that has had the signal peptide and propeptide removed. UniProtKB:P12644, 293-408." [PRO:DNx, Reactome:R-HSA-8858573, Reactome:R-HSA-8956775]

organism-modification


PR:000036511
bone morphogenetic protein 4 isoform 1, mature form (human)
hBMP4/iso:1/mature
"A bone morphogenetic protein 4 isoform 1, mature form in human. UniProtKB:P12644-1, 293-408." [PMID:11401399, PMID:12141440, PMID:12805376, PMID:14660436, PMID:14749725, PMID:9804553, PRO:CNA]
Yes
organism-modification


PR:000072824
bone morphogenetic protein 4, mature phosphorylated form (human)
hBMP4/mature/PhosRes+
"A bone morphogenetic protein 4 (human) that has had the signal peptide and propeptide removed, and that includes at least one phosphorylated residue. UniProtKB:P12644, 293-408, MOD:00696." [PRO:DNx, Reactome:R-HSA-8956944]

organism-modification


PR:000072824
bone morphogenetic protein 4, mature phosphorylated form (human)
hBMP4/mature/PhosRes+
"A bone morphogenetic protein 4 (human) that has had the signal peptide and propeptide removed, and that includes at least one phosphorylated residue. UniProtKB:P12644, 293-408, MOD:00696." [PRO:DNx, Reactome:R-HSA-8956944]

Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036511 hBMP4/iso:1/mature
UniProtKB:P12644-1, 293-408		 acts_upstream_of_or_withinGO:0001649 osteoblast differentiation PMID:14749725
GO:0001657 ureteric bud development PMID:12141440
GO:0001934 positive regulation of protein phosphorylation PMID:14749725
GO:0007498 mesoderm development PMID:9804553
GO:0030509 BMP signaling pathway PMID:12805376
enablesGO:0005102 signaling receptor binding PMID:11401399; PMID:14660436
GO:0042803 protein homodimerization activity PMID:12805376
located_inGO:0005615 extracellular space PMID:12805376
PR:P12644-1 hBMP4/iso:1 acts_upstream_of_or_withinGO:0007498 mesoderm development PMID:9804553
located_inGO:0005622 intracellular anatomical structure PMID:12805376