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Protein Ontology report - insulin-degrading enzyme (human)
PR:P14735 - http://purl.obolibrary.org/obo/PR_P14735
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P14735   
  PRO nameinsulin-degrading enzyme (human) 
  Synonyms
PRO-Short-label: EXACT:hIDE
Gene-based: RELATED:IDE
Other: EXACT:abeta-degrading protease (human) | insulin protease (human) | insulinase (human) | insulysin (human)
  Definition"An insulin-degrading enzyme that is encoded in the genome of human." [PRO:DNx, UniProtKB:P14735
  PRO Categoryorganism-gene 
  ParentPR:000008886 insulin-degrading enzyme
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:5381 IDE (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P14735
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:P14735

insulin-degrading enzyme (human)

hIDE


"An insulin-degrading enzyme that is encoded in the genome of human." [PRO:DNx, UniProtKB:P14735]


organism-sequence



PR:P14735-1

insulin-degrading enzyme isoform 1 (human)

hIDE/iso:1


"An insulin-degrading enzyme isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P14735-2

insulin-degrading enzyme isoform h2 (human)

hIDE/iso:h2


"An insulin-degrading enzyme (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P14735-2." [PRO:DNx, UniProtKB:P14735]


organism-modification



PR:000047941

insulin-degrading enzyme ubiquitinated form (human)

hIDE/UbiqLys+


"An insulin-degrading enzyme (human) that includes at least one ubiquitinated lysine. UniProtKB:P14735, MOD:01148." [PRO:DNx, Reactome:R-HSA-6783095]


organism-modification



PR:000077933

insulin-degrading enzyme methylated 1 (human)

hIDE/Me:1


"An insulin-degrading enzyme (human) that has been methylated on the residue at the position equivalent to Cys-974 of the amino acid sequence represented by UniProtKB:P14735-1. Example: UniProtKB:P14735-1, Cys-974, MOD:00660." [IEDB_epitope:1012645, IEDB_epitope:1014571, PRO:DNx]


organism-modification



PR:000078388

insulin-degrading enzyme deaminated 1 (human)

hIDE/Deam:1


"An insulin-degrading enzyme (human) that has been deaminated on the residue at the position equivalent to Asn-805 of the amino acid sequence represented by UniProtKB:P14735-1. Example: UniProtKB:P14735-1, Asn-805, MOD:00684." [IEDB_epitope:494735, PRO:DNx]