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Protein Ontology report - DNA-directed RNA polymerase II subunit RPB1 (human)
PR:P24928 - http://purl.obolibrary.org/obo/PR_P24928
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P24928   
  PRO nameDNA-directed RNA polymerase II subunit RPB1 (human) 
  Synonyms
PRO-Short-label: EXACT:hPOLR2A
Gene-based: RELATED:POLR2 | POLR2A
Other: EXACT:DNA-directed RNA polymerase II subunit A (human) | RNA polymerase II subunit B1 (human) | RNA-directed RNA polymerase II subunit RPB1 (human)
RELATED:3'-5' exoribonuclease (human)
  Definition"A DNA-directed RNA polymerase II subunit RPB1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P24928
  PRO Categoryorganism-gene 
  ParentPR:000012987 DNA-directed RNA polymerase II subunit RPB1
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:9187 POLR2A (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 24                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P24928
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:P24928

DNA-directed RNA polymerase II subunit RPB1 (human)

hPOLR2A


"A DNA-directed RNA polymerase II subunit RPB1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P24928]


organism-sequence



PR:P24928-1

DNA-directed RNA polymerase II subunit RPB1 isoform 1 (human)

hPOLR2A/iso:1


"A DNA-directed RNA polymerase II subunit RPB1 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P24928-2

DNA-directed RNA polymerase II subunit RPB1 isoform h2 (human)

hPOLR2A/iso:h2


"A DNA-directed RNA polymerase II subunit RPB1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24928-2." [PRO:DNx, UniProtKB:P24928]


organism-modification



PR:000048846

DNA-directed RNA polymerase II subunit RPB1 phosphorylated 1 (human)

hPOLR2A/Phos:1


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been post-translationally modified to include phosphoserine at the second and fifth positions of one or more of the C-terminal heptad repeats (YSPTSPS) of the amino acid sequence represented by UniProtKB:P24928. Example: UniProtKB:P24928-1, Ser-1791/Ser-1794, MOD:00046." [PRO:DAN]


organism-modification



PR:000048847

DNA-directed RNA polymerase II subunit RPB1 phosphorylated 2 (human)

hPOLR2A/Phos:2


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been post-translationally modified to include phosphoserine at the second and seventh positions of one or more of the C-terminal heptad repeats (YSPTSPS) of the amino acid sequence represented by UniProtKB:P24928. Example: UniProtKB:P24928-1, Ser-1791/Ser-1796, MOD:00046." [PRO:DAN]


organism-modification



PR:000048848

DNA-directed RNA polymerase II subunit RPB1 phosphorylated 3 (human)

hPOLR2A/Phos:3


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been post-translationally modified to include phosphoserine at the fifth position of one or more of the C-terminal heptad repeats (YSPTSPS) of the amino acid sequence represented by UniProtKB:P24928. Example: UniProtKB:P24928-1, Ser-1794, MOD:00046." [PRO:DAN]


organism-modification



PR:000048849

DNA-directed RNA polymerase II subunit RPB1 phosphorylated 4 (human)

hPOLR2A/Phos:4


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been post-translationally modified to include phosphoserine at the fifth and seventh positions of one or more of the C-terminal heptad repeats (YSPTSPS) of the amino acid sequence represented by UniProtKB:P24928. Example: UniProtKB:P24928-1, Ser-1794/Ser-1796, MOD:00046." [PRO:DAN]


organism-modification



PR:000048850

DNA-directed RNA polymerase II subunit RPB1 phosphoserine(3+) form (human)

hPOLR2A/PhosSer+


"A DNA-directed RNA polymerase II subunit RPB1 (human) that includes at least three phosphorylated serines. UniProtKB:P24928, MOD:00046(3+)." [PRO:DNx, Reactome:R-HSA-6797701]


organism-modification



PR:000062835

DNA-directed RNA polymerase II subunit RPB1 phosphorylated and ubiquitinated 1 (human)

hPOLR2A/PhosUbiq:1


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been phosphorylated on the residues at the positions equivalent to Ser-1843, Ser-1847, Ser-1850, Ser-1857, Ser-1861, Ser-1864, Ser-1868, Ser-1871, Ser-1875, Ser-1878, Ser-1882, Ser-1889, Ser-1892, Ser-1896, Ser-1899, Ser-1906, Ser-1910, Ser-1913, Ser-1917, Ser-1920, Ser-1924, Ser-1927, Ser-1931, and Ser-1934 of the amino acid sequence represented by UniProtKB:P24928-1 and that includes at least one ubiquitinated lysine. Example: UniProtKB:P24928-1, Ser-1843/Ser-1847/Ser-1850/Ser-1857/Ser-1861/Ser-1864/Ser-1868/Ser-1871/Ser-1875/Ser-1878/Ser-1882/Ser-1889/Ser-1892/Ser-1896/Ser-1899/Ser-1906/Ser-1910/Ser-1913/Ser-1917/Ser-1920/Ser-1924/Ser-1927/Ser-1931/Ser-1934, MOD:00046|MOD:01148." [PRO:DNx, Reactome:R-HSA-6781855]


organism-modification



PR:000065812

DNA-directed RNA polymerase II subunit RPB1 deaminated 1 (human)

hPOLR2A/Deam:1


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been deaminated on the residue at the position equivalent to Asn-1129 of the amino acid sequence represented by UniProtKB:P24928-1. Example: UniProtKB:P24928-1, Asn-1129, MOD:00684." [IEDB_epitope:892484, PRO:DNx]


organism-modification



PR:000068532

DNA-directed RNA polymerase II subunit RPB1 cysteinylated 1 (human)

hPOLR2A/Cyst:1


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-233 of the amino acid sequence represented by UniProtKB:P24928-1. Example: UniProtKB:P24928-1, Cys-233, MOD:00765." [IEDB_epitope:1022088, PRO:DNx]


organism-modification



PR:000069055

DNA-directed RNA polymerase II subunit RPB1 deaminated 2 (human)

hPOLR2A/Deam:2


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been deaminated on the residue at the position equivalent to Gln-529 of the amino acid sequence represented by UniProtKB:P24928-1. Example: UniProtKB:P24928-1, Gln-529, MOD:00685." [IEDB_epitope:903157, PRO:DNx]


organism-modification



PR:000069309

DNA-directed RNA polymerase II subunit RPB1 deaminated 3 (human)

hPOLR2A/Deam:3


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been deaminated on the residue at the position equivalent to Asn-704 of the amino acid sequence represented by UniProtKB:P24928-1. Example: UniProtKB:P24928-1, Asn-704, MOD:00684." [IEDB_epitope:2143984, PRO:DNx]


organism-modification



PR:000069563

DNA-directed RNA polymerase II subunit RPB1 methylated 1 (human)

hPOLR2A/Me:1


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been methylated on the residue at the position equivalent to Cys-233 of the amino acid sequence represented by UniProtKB:P24928-1. Example: UniProtKB:P24928-1, Cys-233, MOD:00660." [IEDB_epitope:1022089, PRO:DNx]


organism-modification



PR:000070943

DNA-directed RNA polymerase II subunit RPB1 cysteinylated 2 (human)

hPOLR2A/Cyst:2


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-1050 of the amino acid sequence represented by UniProtKB:P24928-1. Example: UniProtKB:P24928-1, Cys-1050, MOD:00765." [IEDB_epitope:924953, PRO:DNx]


organism-modification



PR:000071132

DNA-directed RNA polymerase II subunit RPB1 deaminated 4 (human)

hPOLR2A/Deam:4


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been deaminated on the residue at the position equivalent to Asn-1077 of the amino acid sequence represented by UniProtKB:P24928-1. Example: UniProtKB:P24928-1, Asn-1077, MOD:00684." [IEDB_epitope:1977279, PRO:DNx]


organism-modification



PR:000072711

DNA-directed RNA polymerase II subunit RPB1 methylated 2 (human)

hPOLR2A/Me:2


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been methylated on the residue at the position equivalent to Cys-1050 of the amino acid sequence represented by UniProtKB:P24928-1. Example: UniProtKB:P24928-1, Cys-1050, MOD:00660." [IEDB_epitope:1035494, PRO:DNx]


organism-modification



PR:000075205

DNA-directed RNA polymerase II subunit RPB1 methylated 3 (human)

hPOLR2A/Me:3


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been methylated on the residue at the position equivalent to Cys-1159 of the amino acid sequence represented by UniProtKB:P24928-1. Example: UniProtKB:P24928-1, Cys-1159, MOD:00660." [IEDB_epitope:1004218, PRO:DNx]


organism-modification



PR:000076360

DNA-directed RNA polymerase II subunit RPB1 deaminated 5 (human)

hPOLR2A/Deam:5


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been deaminated on the residue at the position equivalent to Gln-703 of the amino acid sequence represented by UniProtKB:P24928-1. Example: UniProtKB:P24928-1, Gln-703, MOD:00685." [IEDB_epitope:2143986, PRO:DNx]


organism-modification



PR:000076592

DNA-directed RNA polymerase II subunit RPB1 cysteinylated 3 (human)

hPOLR2A/Cyst:3


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-1470 of the amino acid sequence represented by UniProtKB:P24928-1. Example: UniProtKB:P24928-1, Cys-1470, MOD:00765." [IEDB_epitope:1584161, PRO:DNx]


organism-modification



PR:000082168

DNA-directed RNA polymerase II subunit RPB1 deaminated 6 (human)

hPOLR2A/Deam:6


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been deaminated on the residue at the position equivalent to Gln-403 of the amino acid sequence represented by UniProtKB:P24928-1. Example: UniProtKB:P24928-1, Gln-403, MOD:00685." [IEDB_epitope:1991570, PRO:DNx]


organism-modification



PR:000082181

DNA-directed RNA polymerase II subunit RPB1 deaminated 7 (human)

hPOLR2A/Deam:7


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been deaminated on the residue at the position equivalent to Asn-1172 of the amino acid sequence represented by UniProtKB:P24928-1. Example: UniProtKB:P24928-1, Asn-1172, MOD:00684." [IEDB_epitope:1330955, PRO:DNx]


organism-modification



PR:000084462

DNA-directed RNA polymerase II subunit RPB1 deaminated 8 (human)

hPOLR2A/Deam:8


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been deaminated on the residue at the position equivalent to Gln-700 of the amino acid sequence represented by UniProtKB:P24928-1. Example: UniProtKB:P24928-1, Gln-700, MOD:00685." [IEDB_epitope:2143985, PRO:DNx]


organism-modification



PR:000085867

DNA-directed RNA polymerase II subunit RPB1 phosphorylated 5 (human)

hPOLR2A/Phos:5


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been phosphorylated on the residues at the positions equivalent to Ser-1845, Ser-1847, Ser-1861, Ser-1868, Ser-1875, Ser-1882, Ser-1889, Ser-1896, Ser-1910, Ser-1917, Ser-1924, and Ser-1931 of the amino acid sequence represented by UniProtKB:P24928-1. Example: UniProtKB:P24928-1, Ser-1845/Ser-1847/Ser-1861/Ser-1868/Ser-1875/Ser-1882/Ser-1889/Ser-1896/Ser-1910/Ser-1917/Ser-1924/Ser-1931, MOD:00046." [PRO:DNx, Reactome:R-HSA-6814543]


organism-modification



PR:000085891

DNA-directed RNA polymerase II subunit RPB1 phosphorylated 6 (human)

hPOLR2A/Phos:6


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been phosphorylated on the residues at the positions equivalent to Ser-1843, Ser-1845, Ser-1850, Ser-1857, Ser-1864, Ser-1871, Ser-1878, Ser-1892, Ser-1899, Ser-1906, Ser-1913, Ser-1920, Ser-1927, and Ser-1934 of the amino acid sequence represented by UniProtKB:P24928-1. Example: UniProtKB:P24928-1, Ser-1843/Ser-1845/Ser-1850/Ser-1857/Ser-1864/Ser-1871/Ser-1878/Ser-1892/Ser-1899/Ser-1906/Ser-1913/Ser-1920/Ser-1927/Ser-1934, MOD:00046." [PRO:DNx, Reactome:R-HSA-6810226]


organism-modification



PR:000085902

DNA-directed RNA polymerase II subunit RPB1 phosphorylated 7 (human)

hPOLR2A/Phos:7


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been phosphorylated on the residues at the positions equivalent to Ser-1843, Ser-1847, Ser-1850, Ser-1857, Ser-1861, Ser-1864, Ser-1868, Ser-1871, Ser-1875, Ser-1878, Ser-1882, Ser-1889, Ser-1892, Ser-1896, Ser-1899, Ser-1906, Ser-1910, Ser-1913, Ser-1917, Ser-1920, Ser-1924, Ser-1927, Ser-1931, and Ser-1934 of the amino acid sequence represented by UniProtKB:P24928-1. Example: UniProtKB:P24928-1, Ser-1843/Ser-1847/Ser-1850/Ser-1857/Ser-1861/Ser-1864/Ser-1868/Ser-1871/Ser-1875/Ser-1878/Ser-1882/Ser-1889/Ser-1892/Ser-1896/Ser-1899/Ser-1906/Ser-1910/Ser-1913/Ser-1917/Ser-1920/Ser-1924/Ser-1927/Ser-1931/Ser-1934, MOD:00046." [PRO:DNx, Reactome:R-HSA-113420]


organism-modification



PR:000085941

DNA-directed RNA polymerase II subunit RPB1 phosphorylated 8 (human)

hPOLR2A/Phos:8


"A DNA-directed RNA polymerase II subunit RPB1 (human) that has been phosphorylated on the residues at the positions equivalent to Ser-1843, Ser-1850, Ser-1857, Ser-1864, Ser-1871, Ser-1878, Ser-1892, Ser-1899, Ser-1906, Ser-1913, Ser-1920, Ser-1927, and Ser-1934 of the amino acid sequence represented by UniProtKB:P24928-1. Example: UniProtKB:P24928-1, Ser-1843/Ser-1850/Ser-1857/Ser-1864/Ser-1871/Ser-1878/Ser-1892/Ser-1899/Ser-1906/Ser-1913/Ser-1920/Ser-1927/Ser-1934, MOD:00046." [PRO:DNx, Reactome:R-HSA-77100]