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Protein Ontology report - nitric oxide synthase 3 (human)
PR:P29474 -
http://purl.obolibrary.org/obo/PR_P29474
Protein Forms
Ontology Information
Show OBO stanza
/
GPI
PRO ID
PR:P29474
PRO name
nitric oxide synthase 3 (human)
Synonyms
PRO-Short-label
:
EXACT:
hNOS3
Gene-based
:
RELATED:
NOS3
Other
:
EXACT:
cNOS (human) | EC-NOS (human) | endothelial NOS (human) | eNOS (human) | nitric oxide synthase, endothelial (human) | NOS type III (human) | NOSIII (human)
Definition
"A nitric oxide synthase 3 that is encoded in the genome of human." [PRO:DNx,
UniProtKB:P29474
]
PRO Category
organism-gene
Parent
PR:000011328
nitric oxide synthase 3
PR:000029067
Homo sapiens protein
Gene Template
HGNC:7876
NOS3 (human)
Taxon
NCBITaxon:9606
Homo sapiens
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
0
Organism-Gene
1
Sequence
0
Organism-Sequence
3
Modification
0
Organism-Modification
9
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
UniProtKB:P29474
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Protein Forms
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Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
organism-gene
PR:P29474
nitric oxide synthase 3 (human)
hNOS3
"A nitric oxide synthase 3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P29474]
organism-sequence
PR:P29474-1
nitric oxide synthase 3 isoform h1 (human)
hNOS3/iso:h1
"A nitric oxide synthase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29474-1." [PRO:DNx, UniProtKB:P29474]
organism-sequence
PR:P29474-2
nitric oxide synthase 3 isoform heNOS13C (human)
hNOS3/iso:heNOS13C
"A nitric oxide synthase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29474-2." [PRO:DNx, UniProtKB:P29474]
organism-sequence
PR:P29474-3
nitric oxide synthase 3 isoform heNOS13B (human)
hNOS3/iso:heNOS13B
"A nitric oxide synthase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29474-3." [PRO:DNx, UniProtKB:P29474]
organism-modification
PR:000045739
nitric oxide synthase 3 phosphorylated 1 (human)
hNOS3/Phos:1
"A nitric oxide synthase 3 (human) that has been phosphorylated on the residue at the position equivalent to Ser-1177 of the amino acid sequence represented by UniProtKB:P29474-1. Example: UniProtKB:P29474-1, Ser-1177, MOD:00046." [iPTMnet:P29474, PMID:10376603, PMID:12446767, PMID:12791703]
organism-modification
PR:000048622
nitric oxide synthase 3, initiator methionine removed form (human)
hNOS3/InitMet-
"A nitric oxide synthase 3 (human) that has had the initiator methionine removed. UniProtKB:P29474, 2-1203." [PRO:DNx, Reactome:R-HSA-202114]
organism-modification
PR:000061483
nitric oxide synthase 3, initiator methionine removed myristoylated 1 (human)
hNOS3/InitMet-/Myr:1
"A nitric oxide synthase 3 (human) that has had the initiator methionine removed and that has been myristoylated on the residue at the position equivalent to Gly-2 of the amino acid sequence represented by UniProtKB:P29474-1. Example: UniProtKB:P29474-1, 2-1203, Gly-2, MOD:00068." [PRO:DNx, Reactome:R-HSA-203687, Reactome:R-HSA-534995]
organism-modification
PR:000061586
nitric oxide synthase 3, initiator methionine removed myristoylated and palmitoylated 1 (human)
hNOS3/InitMet-/MyrPalm:1
"A nitric oxide synthase 3 (human) that has had the initiator methionine removed and that has been myristoylated on the residue at the position equivalent to Gly-2 and palmitoylated on the residues at the positions equivalent to Cys-15 and Cys-26 of the amino acid sequence represented by UniProtKB:P29474-1. Example: UniProtKB:P29474-1, 2-1203, Gly-2, MOD:00068|Cys-15/Cys-26, MOD:00115." [PRO:DNx, Reactome:R-HSA-203769, Reactome:R-HSA-534993, Reactome:R-HSA-535007]
organism-modification
PR:000062632
nitric oxide synthase 3, initiator methionine removed myristoylated, palmitoylated, and phosphorylated 1 (human)
hNOS3/InitMet-/MyrPalmPhos:1
"A nitric oxide synthase 3 (human) that has had the initiator methionine removed and that has been myristoylated on the residue at the position equivalent to Gly-2, palmitoylated on the residues at the positions equivalent to Cys-15 and Cys-26, and phosphorylated on the residue at the position equivalent to Ser-1177 of the amino acid sequence represented by UniProtKB:P29474-1. Example: UniProtKB:P29474-1, 2-1203, Gly-2, MOD:00068|Cys-15/Cys-26, MOD:00115|Ser-1177, MOD:00046." [PRO:DNx, Reactome:R-HSA-202139]
organism-modification
PR:000085916
nitric oxide synthase 3, initiator methionine removed myristoylated, palmitoylated, and phosphorylated 2 (human)
hNOS3/InitMet-/MyrPalmPhos:2
"A nitric oxide synthase 3 (human) that has had the initiator methionine removed and that has been myristoylated on the residue at the position equivalent to Gly-2, palmitoylated on the residues at the positions equivalent to Cys-15 and Cys-26, and phosphorylated on the residues at the positions equivalent to Ser-1177 and Ser-1179 of the amino acid sequence represented by UniProtKB:P29474-1. Example: UniProtKB:P29474-1, 2-1203, Gly-2, MOD:00068|Cys-15/Cys-26, MOD:00115|Ser-1177/Ser-1179, MOD:00046." [PRO:DNx, Reactome:R-HSA-9860783]
organism-modification
PR:000085948
nitric oxide synthase 3, initiator methionine removed myristoylated, palmitoylated, and phosphorylated 3 (human)
hNOS3/InitMet-/MyrPalmPhos:3
"A nitric oxide synthase 3 (human) that has had the initiator methionine removed and that has been myristoylated on the residue at the position equivalent to Gly-2, palmitoylated on the residues at the positions equivalent to Cys-15 and Cys-26, and phosphorylated on the residue at the position equivalent to Ser-633 of the amino acid sequence represented by UniProtKB:P29474-1. Example: UniProtKB:P29474-1, 2-1203, Gly-2, MOD:00068|Cys-15/Cys-26, MOD:00115|Ser-633, MOD:00046." [PRO:DNx, Reactome:R-HSA-9861341]
organism-modification
PR:000056330
nitric oxide synthase 3 O-glycosylated 1 (human)
hNOS3/OGlyco:1
"A nitric oxide synthase 3 (human) that has been O-glycosylated at the residue equivalent to Ser-78 of the amino acid sequence represented by UniProtKB:P29474-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P29474-1, Ser-78, MOD:00002~GNO:G58001LT." [GlyGen:P29474-1, PMID:30459171, PRO:DNx]
organism-modification
PR:000075289
nitric oxide synthase 3 deaminated 1 (human)
hNOS3/Deam:1
"A nitric oxide synthase 3 (human) that has been deaminated on the residue at the position equivalent to Asn-403 of the amino acid sequence represented by UniProtKB:P29474-1. Example: UniProtKB:P29474-1, Asn-403, MOD:00684." [IEDB_epitope:1982414, PRO:DNx]