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Protein Ontology report - nitric oxide synthase 3 (human)
PR:P29474 - http://purl.obolibrary.org/obo/PR_P29474
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P29474   
  PRO namenitric oxide synthase 3 (human) 
  Synonyms
PRO-Short-label: EXACT:hNOS3
Gene-based: RELATED:NOS3
Other: EXACT:cNOS (human) | EC-NOS (human) | endothelial NOS (human) | eNOS (human) | nitric oxide synthase, endothelial (human) | NOS type III (human) | NOSIII (human)
  Definition"A nitric oxide synthase 3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P29474
  PRO Categoryorganism-gene 
  ParentPR:000011328 nitric oxide synthase 3
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:7876 NOS3 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P29474
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:P29474

nitric oxide synthase 3 (human)

hNOS3


"A nitric oxide synthase 3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P29474]


organism-sequence



PR:P29474-1

nitric oxide synthase 3 isoform h1 (human)

hNOS3/iso:h1


"A nitric oxide synthase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29474-1." [PRO:DNx, UniProtKB:P29474]


organism-sequence



PR:P29474-2

nitric oxide synthase 3 isoform heNOS13C (human)

hNOS3/iso:heNOS13C


"A nitric oxide synthase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29474-2." [PRO:DNx, UniProtKB:P29474]


organism-sequence



PR:P29474-3

nitric oxide synthase 3 isoform heNOS13B (human)

hNOS3/iso:heNOS13B


"A nitric oxide synthase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29474-3." [PRO:DNx, UniProtKB:P29474]


organism-modification



PR:000045739

nitric oxide synthase 3 phosphorylated 1 (human)

hNOS3/Phos:1


"A nitric oxide synthase 3 (human) that has been phosphorylated on the residue at the position equivalent to Ser-1177 of the amino acid sequence represented by UniProtKB:P29474-1. Example: UniProtKB:P29474-1, Ser-1177, MOD:00046." [iPTMnet:P29474, PMID:10376603, PMID:12446767, PMID:12791703]


organism-modification



PR:000048622

nitric oxide synthase 3, initiator methionine removed form (human)

hNOS3/InitMet-


"A nitric oxide synthase 3 (human) that has had the initiator methionine removed. UniProtKB:P29474, 2-1203." [PRO:DNx, Reactome:R-HSA-202114]


organism-modification



PR:000061483

nitric oxide synthase 3, initiator methionine removed myristoylated 1 (human)

hNOS3/InitMet-/Myr:1


"A nitric oxide synthase 3 (human) that has had the initiator methionine removed and that has been myristoylated on the residue at the position equivalent to Gly-2 of the amino acid sequence represented by UniProtKB:P29474-1. Example: UniProtKB:P29474-1, 2-1203, Gly-2, MOD:00068." [PRO:DNx, Reactome:R-HSA-203687, Reactome:R-HSA-534995]


organism-modification



PR:000061586

nitric oxide synthase 3, initiator methionine removed myristoylated and palmitoylated 1 (human)

hNOS3/InitMet-/MyrPalm:1


"A nitric oxide synthase 3 (human) that has had the initiator methionine removed and that has been myristoylated on the residue at the position equivalent to Gly-2 and palmitoylated on the residues at the positions equivalent to Cys-15 and Cys-26 of the amino acid sequence represented by UniProtKB:P29474-1. Example: UniProtKB:P29474-1, 2-1203, Gly-2, MOD:00068|Cys-15/Cys-26, MOD:00115." [PRO:DNx, Reactome:R-HSA-203769, Reactome:R-HSA-534993, Reactome:R-HSA-535007]


organism-modification



PR:000062632

nitric oxide synthase 3, initiator methionine removed myristoylated, palmitoylated, and phosphorylated 1 (human)

hNOS3/InitMet-/MyrPalmPhos:1


"A nitric oxide synthase 3 (human) that has had the initiator methionine removed and that has been myristoylated on the residue at the position equivalent to Gly-2, palmitoylated on the residues at the positions equivalent to Cys-15 and Cys-26, and phosphorylated on the residue at the position equivalent to Ser-1177 of the amino acid sequence represented by UniProtKB:P29474-1. Example: UniProtKB:P29474-1, 2-1203, Gly-2, MOD:00068|Cys-15/Cys-26, MOD:00115|Ser-1177, MOD:00046." [PRO:DNx, Reactome:R-HSA-202139]


organism-modification



PR:000085916

nitric oxide synthase 3, initiator methionine removed myristoylated, palmitoylated, and phosphorylated 2 (human)

hNOS3/InitMet-/MyrPalmPhos:2


"A nitric oxide synthase 3 (human) that has had the initiator methionine removed and that has been myristoylated on the residue at the position equivalent to Gly-2, palmitoylated on the residues at the positions equivalent to Cys-15 and Cys-26, and phosphorylated on the residues at the positions equivalent to Ser-1177 and Ser-1179 of the amino acid sequence represented by UniProtKB:P29474-1. Example: UniProtKB:P29474-1, 2-1203, Gly-2, MOD:00068|Cys-15/Cys-26, MOD:00115|Ser-1177/Ser-1179, MOD:00046." [PRO:DNx, Reactome:R-HSA-9860783]


organism-modification



PR:000085948

nitric oxide synthase 3, initiator methionine removed myristoylated, palmitoylated, and phosphorylated 3 (human)

hNOS3/InitMet-/MyrPalmPhos:3


"A nitric oxide synthase 3 (human) that has had the initiator methionine removed and that has been myristoylated on the residue at the position equivalent to Gly-2, palmitoylated on the residues at the positions equivalent to Cys-15 and Cys-26, and phosphorylated on the residue at the position equivalent to Ser-633 of the amino acid sequence represented by UniProtKB:P29474-1. Example: UniProtKB:P29474-1, 2-1203, Gly-2, MOD:00068|Cys-15/Cys-26, MOD:00115|Ser-633, MOD:00046." [PRO:DNx, Reactome:R-HSA-9861341]


organism-modification



PR:000056330

nitric oxide synthase 3 O-glycosylated 1 (human)

hNOS3/OGlyco:1


"A nitric oxide synthase 3 (human) that has been O-glycosylated at the residue equivalent to Ser-78 of the amino acid sequence represented by UniProtKB:P29474-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P29474-1, Ser-78, MOD:00002~GNO:G58001LT." [GlyGen:P29474-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000075289

nitric oxide synthase 3 deaminated 1 (human)

hNOS3/Deam:1


"A nitric oxide synthase 3 (human) that has been deaminated on the residue at the position equivalent to Asn-403 of the amino acid sequence represented by UniProtKB:P29474-1. Example: UniProtKB:P29474-1, Asn-403, MOD:00684." [IEDB_epitope:1982414, PRO:DNx]