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Protein Ontology report - TGF-beta receptor type-2 isoform RII-1 (human)
PR:P37173-1 - http://purl.obolibrary.org/obo/PR_P37173-1
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P37173-1   
  PRO nameTGF-beta receptor type-2 isoform RII-1 (human) 
  Synonyms
PRO-Short-label: EXACT:hTGFBR2/iso:RII-1
  Definition"A TGF-beta receptor type-2 isoform RII-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P37173] 
  CommentRequested by=PubChem. 
  PRO Categoryorganism-sequence 
  ParentPR:000000048 TGF-beta receptor type-2 isoform RII-1
PR:P37173 TGF-beta receptor type-2 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence0                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P37173-1
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
organism-sequence


PR:P37173-1
TGF-beta receptor type-2 isoform RII-1 (human)
hTGFBR2/iso:RII-1
"A TGF-beta receptor type-2 isoform RII-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P37173]

organism-modification


PR:000036408
TGF-beta receptor type-2 isoform RII-1, signal peptide removed form (human)
hTGFBR2/iso:RII-1/SigPep-
"A TGF-beta receptor type-2 isoform RII-1, signal peptide removed form in human. UniProtKB:P37173-1, 23-567." [PMID:11483955, PMID:11850637, PMID:1310899, PMID:1850637, PMID:8774881, PRO:CNA]
Yes
organism-modification


PR:000025962
TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1 (human)
hTGFBR2/iso:RII-1/SigPep-/Phos:1
"A TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1 in human. UniProtKB:P37173-1, 23-567, Ser-213/Ser-409, MOD:00046|Tyr-259/Tyr-336/Tyr-424, MOD:00048." [PID:TGFB/TGFBR2/TGFBR1]

Yes
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hTGFBR2/iso:RII-1 forms found in complexes   

hTGFBR2/iso:RII-1 Component
 Complexes
PR:000025962 hTGFBR2/iso:RII-1/SigPep-/Phos:1 PR:000025963 transforming growth factor beta type II receptor homodimeric complex phosphorylated form (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036408 hTGFBR2/iso:RII-1/SigPep-
UniProtKB:P37173-1, 23-567		 acts_upstream_of_or_withinGO:0007179 transforming growth factor beta receptor signaling pathway PMID:11483955
GO:0007181 transforming growth factor beta receptor complex assembly PMID:1310899; PMID:8774881
enablesGO:0005026 transforming growth factor beta receptor activity, type II PMID:11483955
GO:0005515 protein binding with PR:000000634 TGFB3/iso:1/Clv:1 PMID:1850637
GO:0005515 protein binding PMID:1850637
GO:0050431 transforming growth factor beta binding PMID:11850637; PMID:1310899
located_inGO:0016020 membrane PMID:1310899