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Protein Ontology report - TGF-beta receptor type-2 isoform RII-1 (human)
PR:P37173-1 - http://purl.obolibrary.org/obo/PR_P37173-1
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P37173-1   
  PRO nameTGF-beta receptor type-2 isoform RII-1 (human) 
  Synonyms
PRO-Short-label: EXACT:hTGFBR2/iso:RII-1
  Definition"A TGF-beta receptor type-2 isoform RII-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P37173] 
  CommentRequested by=PubChem. 
  PRO Categoryorganism-sequence 
  ParentPR:000000048 TGF-beta receptor type-2 isoform RII-1
PR:P37173 TGF-beta receptor type-2 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence0                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P37173-1
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
organism-sequence


PR:P37173-1 TGF-beta receptor type-2 isoform RII-1 (human)
hTGFBR2/iso:RII-1

organism-modification


PR:000036408 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form (human)
hTGFBR2/iso:RII-1/SigPep-
Yes
organism-modification


PR:000025962 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1 (human)
hTGFBR2/iso:RII-1/SigPep-/Phos:1

Yes
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hTGFBR2/iso:RII-1 forms found in complexes   

hTGFBR2/iso:RII-1 Component
 Complexes
PR:000025962 hTGFBR2/iso:RII-1/SigPep-/Phos:1 PR:000025963 transforming growth factor beta type II receptor homodimeric complex phosphorylated form (human)
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0007179 transforming growth factor beta receptor signaling pathwayPR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:11483955
GO:0007181 transforming growth factor beta receptor complex assemblyPR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1310899; PMID:8774881

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0005026 transforming growth factor beta receptor activity, type IIPR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:11483955
GO:0005515 protein bindingPR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
GO:0050431 transforming growth factor beta bindingPR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:11850637; PMID:1310899

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0016020 membranePR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1310899