back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - cyclin-dependent kinase 4 inhibitor B (human)
PR:P42772 - http://purl.obolibrary.org/obo/PR_P42772
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:P42772   
  PRO namecyclin-dependent kinase 4 inhibitor B (human) 
  Synonyms
PRO-Short-label: EXACT:hCDKN2B
Gene-based: RELATED:CDKN2B | MTS2
Other: EXACT:MTS-2 (human) | multiple tumor suppressor 2 (human) | p14-INK4b (human) | p15-INK4b (human) | p15INK4B (human)
  Definition"A cyclin-dependent kinase 4 inhibitor B that is encoded in the genome of human." [PRO:CNA, UniProtKB:P42772] 
  PRO Categoryorganism-gene 
  ParentPR:000000093 cyclin-dependent kinase 4 inhibitor B
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:1788 CDKN2B (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
UniProtKB:P42772
Back to top
Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:P42772 cyclin-dependent kinase 4 inhibitor B (human)
hCDKN2B

organism-sequence


PR:000000269 cyclin-dependent kinase 4 inhibitor B sequence variant G47E (human)
hCDKN2B/var:G47E

organism-sequence


PR:000000270 cyclin-dependent kinase 4 inhibitor B sequence variant A50V (human)
hCDKN2B/var:A50V

organism-sequence


PR:P42772-1 cyclin-dependent kinase 4 inhibitor B isoform 1 (human)
hCDKN2B/iso:1
Yes
organism-sequence


PR:P42772-2 cyclin-dependent kinase 4 inhibitor B isoform h2 (human)
hCDKN2B/iso:h2

Back to top
Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activityPR:P42772-1 hCDKN2B/iso:1 PMID:8078588
GO:0008285 negative regulation of cell population proliferationPR:P42772-1 hCDKN2B/iso:1 PMID:8078588
GO:0051726 regulation of cell cyclePR:P42772-1 hCDKN2B/iso:1 PMID:8078588

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activityPR:P42772-1 hCDKN2B/iso:1 PMID:8078588
GO:0005515 protein bindingPR:P42772-1 hCDKN2B/iso:1 PMID:16169070