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Protein Ontology report - tyrosine-protein kinase ZAP-70 (human)
PR:P43403 - http://purl.obolibrary.org/obo/PR_P43403
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P43403   
  PRO nametyrosine-protein kinase ZAP-70 (human) 
  Synonyms
PRO-Short-label: EXACT:hZAP70
Gene-based: RELATED:SRK | ZAP70
Other: EXACT:70 kDa zeta-chain associated protein (human) | Syk-related tyrosine kinase (human)
  Definition"A tyrosine-protein kinase ZAP-70 that is encoded in the genome of human." [PRO:CL, UniProtKB:P43403
  PRO Categoryorganism-gene 
  ParentPR:000003064 tyrosine-protein kinase ZAP-70
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:12858 ZAP70 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P43403
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:P43403

tyrosine-protein kinase ZAP-70 (human)

hZAP70


"A tyrosine-protein kinase ZAP-70 that is encoded in the genome of human." [PRO:CL, UniProtKB:P43403]


organism-sequence



PR:P43403-1

tyrosine-protein kinase ZAP-70 isoform 1 (human)

hZAP70/iso:1


"A tyrosine-protein kinase ZAP-70 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000036629

tyrosine-protein kinase ZAP-70 isoform 1 phosphorylated 1 (human)

hZAP70/iso:1/Phos:1


"A tyrosine-protein kinase ZAP-70 isoform 1 phosphorylated 1 in human." [PMID:9269777, PRO:CL]

Yes

organism-sequence



PR:P43403-2

tyrosine-protein kinase ZAP-70 isoform 2 (human)

hZAP70/iso:2


"A tyrosine-protein kinase ZAP-70 isoform 2 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P43403-3

tyrosine-protein kinase ZAP-70 isoform h3 (human)

hZAP70/iso:h3


"A tyrosine-protein kinase ZAP-70 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43403-3." [PRO:DNx, UniProtKB:P43403]


organism-modification



PR:000045788

tyrosine-protein kinase ZAP-70 phosphorylated 1 (human)

hZAP70/Phos:1


"A tyrosine-protein kinase ZAP-70 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-319 of the amino acid sequence represented by UniProtKB:P43403-1. Example: UniProtKB:P43403-1, Tyr-319, MOD:00048." [iPTMnet:P43403, PMID:10202147, PMID:10318843, PMID:15292262]


organism-modification



PR:000049722

tyrosine-protein kinase ZAP-70 phosphorylated 2 (human)

hZAP70/Phos:2


"A tyrosine-protein kinase ZAP-70 (human) that has been phosphorylated on residues at positions equivalent to Thr-315 and Thr-493 of the amino acid sequence represented by UniProtKB:P43403-1. Example: UniProtKB:P43403-1, Tyr-315/Tyr-493, MOD:00048." [PRO:DNx, Reactome:R-HSA-202252]


organism-modification



PR:000049723

tyrosine-protein kinase ZAP-70 phosphorylated 3 (human)

hZAP70/Phos:3


"A tyrosine-protein kinase ZAP-70 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-493 of the amino acid sequence represented by UniProtKB:P43403-1. Example: UniProtKB:P43403-1, Tyr-493, MOD:00048." [PRO:DNx, Reactome:R-HSA-202368]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036629 hZAP70/iso:1/Phos:1 acts_upstream_of_or_withinGO:0090630 activation of GTPase activity PMID:9269777