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Protein Ontology report - transcriptional coactivator YAP1 isoform 3 (human)
PR:P46937-3 - http://purl.obolibrary.org/obo/PR_P46937-3
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P46937-3   
  PRO nametranscriptional coactivator YAP1 isoform 3 (human) 
  Synonyms
PRO-Short-label: EXACT:hYAP1/iso:3
Other: EXACT:transcriptional coactivator YAP1 isoform YAP1-1beta (human)
  Definition"A transcriptional coactivator YAP1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P46937-3." [PRO:DNx, UniProtKB:P46937] 
  PRO Categoryorganism-sequence 
  ParentPR:P46937 transcriptional coactivator YAP1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence0                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P46937-3
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
organism-sequence


PR:P46937-3
transcriptional coactivator YAP1 isoform 3 (human)
hYAP1/iso:3
"A transcriptional coactivator YAP1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P46937-3." [PRO:DNx, UniProtKB:P46937]

organism-modification


PR:000037507
transcriptional coactivator YAP1 isoform 3 unphosphorylated 1 (human)
hYAP1/iso:3/UnPhos:1
"A transcriptional coactivator YAP1 isoform 3 (human) that lacks a phosphorylated Tyr residue at position 357. UniProtKB:P46937-3, Tyr-357, PR:000026291." [PMID:21214929, PMID:21945154, PRO:KER]
Yes
organism-modification


PR:000037508
transcriptional coactivator YAP1 isoform 3 phosphorylated 1 (human)
hYAP1/iso:3/Phos:1
"A transcriptional coactivator YAP1 isoform 3 (human) that has been phosphorylated on a Tyr residue at position 357. UniProtKB:P46937-3, Tyr-357, MOD:00048." [PMID:21214929, PMID:21945154, PRO:KER]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000037507 hYAP1/iso:3/UnPhos:1
UniProtKB:P46937-3, Tyr-357, PR:000026291		 enablesGO:0005515 protein binding with PR:O15350 hTP73 PMID:21214929; PMID:21562856
PR:000037508 hYAP1/iso:3/Phos:1
UniProtKB:P46937-3, Tyr-357, MOD:00048		 associated_with_disease_progressionDO:10652 Alzheimer's disease PMID:21562856
enablesincreased GO:0005515 protein binding with PR:O15350 hTP73 PMID:21214929; PMID:21562856
located_inD162 cancer PMID:21214929
GO:0005634 nucleus PMID:21562856