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Protein Ontology report - solute carrier family 12 member 1 (mouse)
PR:P55014 - http://purl.obolibrary.org/obo/PR_P55014
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:P55014   
  PRO namesolute carrier family 12 member 1 (mouse) 
  Synonyms
PRO-Short-label: EXACT:mSLC12A1
Gene-based: RELATED:Nkcc2 | Slc12a1
Other: EXACT:BSC1 (mouse) | bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1 (mouse) | kidney-specific Na-K-Cl symporter (mouse) | mNKCC2 | Na-K-2Cl cotransporter 2 (mouse)
  Definition"A solute carrier family 12 member 1 that is encoded in the genome of mouse." [OMA:P55014, PRO:DNx] 
  PRO Categoryorganism-gene 
  ParentPR:000014924 solute carrier family 12 member 1
PR:000029032 Mus musculus protein
  Gene TemplateMGI:103150 Slc12a1 (mouse)
  TaxonNCBITaxon:10090 Mus musculus
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P55014
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:P55014

solute carrier family 12 member 1 (mouse)

mSLC12A1


"A solute carrier family 12 member 1 that is encoded in the genome of mouse." [OMA:P55014, PRO:DNx]


organism-sequence



PR:P55014-1

solute carrier family 12 member 1 isoform A (mouse)

mSlc12a1/iso:A


"A solute carrier family 12 member 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55014-1." [PRO:DNx, UniProtKB:P55014]

Yes

organism-sequence



PR:P55014-2

solute carrier family 12 member 1 isoform A4 (mouse)

mSlc12a1/iso:A4


"A solute carrier family 12 member 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55014-2." [PRO:DNx, UniProtKB:P55014]


organism-sequence



PR:P55014-3

solute carrier family 12 member 1 isoform B (mouse)

mSlc12a1/iso:B


"A solute carrier family 12 member 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55014-3." [PRO:DNx, UniProtKB:P55014]


organism-sequence



PR:P55014-4

solute carrier family 12 member 1 isoform F (mouse)

mSlc12a1/iso:F


"A solute carrier family 12 member 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55014-4." [PRO:DNx, UniProtKB:P55014]

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P55014-1 mSlc12a1/iso:A acts_upstream_of_or_withinGO:0070886 positive regulation of calcineurin-NFAT signaling cascade MGI_ref:4947009; PMID:21228109
GO:0071475 cellular hyperosmotic salinity response MGI_ref:4947009; PMID:21228109
PR:P55014-4 mSlc12a1/iso:F enablesGO:0005515 protein binding with PR:000044370|PR:G1JLS7|PR:Q9Z1W9-1 MGI_ref:5538439; PMID:24133122
GO:0008511 sodium:potassium:chloride symporter activity MGI_ref:5538439; PMID:24133122