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Protein Ontology report - transforming protein RhoA (human)
PR:P61586 - http://purl.obolibrary.org/obo/PR_P61586
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P61586   
  PRO nametransforming protein RhoA (human) 
  Synonyms
PRO-Short-label: EXACT:hRHOA
Gene-based: RELATED:ARH12 | ARHA | RHO12 | RHOA
Other: EXACT:h12 (human) | Rho cDNA clone 12 (human)
  Definition"A GTP-binding protein RhoA that is encoded in the genome of human." [PRO:CNA, UniProtKB:P61586] 
  PRO Categoryorganism-gene 
  ParentPR:000000176 GTP-binding protein RhoA
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:667 RHOA (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P61586
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:P61586
transforming protein RhoA (human)
hRHOA
"A GTP-binding protein RhoA that is encoded in the genome of human." [PRO:CNA, UniProtKB:P61586]

organism-sequence


PR:P61586-1
transforming protein RhoA isoform 1 (human)
hRHOA/iso:1
"A GTP-binding protein RhoA isoform 1 that is encoded in the genome of human." [PRO:CNA]

organism-modification


PR:000036520
GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester-containing 1 (human)
hRHOA/iso:1/IpCysEst:1
"A GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester-containing 1 in human. UniProtKB:P61586-1, 1-190, Cys-190, MOD:01119." [PMID:1383236, PMID:16773203, PRO:CNA, PRO:DAN]
Yes
organism-modification


PR:000077673
transforming protein RhoA, mature form (human)
hRHOA/mature
"A transforming protein RhoA (human) that has had the propeptide removed. UniProtKB:P61586, 1-190." [PRO:DNx, Reactome:R-HSA-194510, Reactome:R-HSA-194866, Reactome:R-HSA-2134503, Reactome:R-HSA-5672082, Reactome:R-HSA-6804971, Reactome:R-HSA-6804980]

organism-modification


PR:000036520
GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester-containing 1 (human)
hRHOA/iso:1/IpCysEst:1
"A GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester-containing 1 in human. UniProtKB:P61586-1, 1-190, Cys-190, MOD:01119." [PMID:1383236, PMID:16773203, PRO:CNA, PRO:DAN]
Yes
organism-modification


PR:000084770
transforming protein RhoA cysteinylated 1 (human)
hRHOA/Cyst:1
"A transforming protein RhoA (human) that has been cysteinylated on the residue at the position equivalent to Cys-159 of the amino acid sequence represented by UniProtKB:P61586. UniProtKB:P61586, Cys-159, MOD:00765." [IEDB_epitope:2124861, PRO:DNx]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036520 hRHOA/iso:1/IpCysEst:1
UniProtKB:P61586-1, 1-190, Cys-190, MOD:01119		 acts_upstream_of_or_withinGO:0030036 actin cytoskeleton organization PMID:16773203
GO:0043123 positive regulation of canonical NF-kappaB signal transduction PMID:12761501
GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction PMID:12761501
located_inGO:0005886 plasma membrane PMID:16773203