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Protein Ontology report - E3 ubiquitin-protein ligase RBX1 (human)
PR:P62877 - http://purl.obolibrary.org/obo/PR_P62877
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:P62877   
  PRO nameE3 ubiquitin-protein ligase RBX1 (human) 
  Synonyms
PRO-Short-label: EXACT:hRBX1
Gene-based: RELATED:RBX1 | RNF75 | ROC1
Other: EXACT:E3 ubiquitin-protein transferase RBX1 (human) | protein ZYP (human) | Rbx1 (human) | regulator of cullins 1 (human) | RING finger protein 75 (human) | RING-box protein 1 (human)
  Definition"An E3 ubiquitin-protein ligase RBX1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P62877] 
  PRO Categoryorganism-gene 
  ParentPR:000000043 E3 ubiquitin-protein ligase RBX1
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:9928 RBX1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P62877
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:P62877
E3 ubiquitin-protein ligase RBX1 (human)
hRBX1
"An E3 ubiquitin-protein ligase RBX1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P62877]

organism-sequence


PR:P62877-1
E3 ubiquitin-protein ligase RBX1 isoform 1 (human)
hRBX1/iso:1
"An E3 ubiquitin-protein ligase RBX1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
Yes
organism-modification


PR:000026756
E3 ubiquitin-protein ligase RBX1, initiator methionine removed form (human)
hRBX1/InitMet-
"An E3 ubiquitin-protein ligase RBX1, initiator methionine removed form in human. UniProtKB:P62877, 2-108." [PRO:DNx]

Yes
organism-modification


PR:000065210
E3 ubiquitin-protein ligase RBX1 methylated 1 (human)
hRBX1/Me:1
"An E3 ubiquitin-protein ligase RBX1 (human) that has been methylated on the residue at the position equivalent to Cys-83 of the amino acid sequence represented by UniProtKB:P62877. UniProtKB:P62877, Cys-83, MOD:00660." [IEDB_epitope:1017283, IEDB_epitope:1035364, PRO:DNx]

organism-modification


PR:000065917
E3 ubiquitin-protein ligase RBX1 cysteinylated 1 (human)
hRBX1/Cyst:1
"An E3 ubiquitin-protein ligase RBX1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-75 of the amino acid sequence represented by UniProtKB:P62877. UniProtKB:P62877, Cys-75, MOD:00765." [IEDB_epitope:926381, PRO:DNx]

organism-modification


PR:000068175
E3 ubiquitin-protein ligase RBX1 cysteinylated 2 (human)
hRBX1/Cyst:2
"An E3 ubiquitin-protein ligase RBX1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-83 of the amino acid sequence represented by UniProtKB:P62877. UniProtKB:P62877, Cys-83, MOD:00765." [IEDB_epitope:1011802, IEDB_epitope:881271, PRO:DNx]

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hRBX1 forms found in complexes   

hRBX1 Component
 Complexes
PR:000026756 hRBX1/InitMet- PR:000026771 SCF beta-TrCP complex (human)
PR:000037513 FBXO4:CRYAB:Skp1:Cul1:Rbx1 complex (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P62877-1 hRBX1/iso:1 acts_upstream_of_or_withinGO:0006511 ubiquitin-dependent protein catabolic process PMID:10230407
GO:0006606 protein import into nucleus PMID:11027288
GO:0045116 protein neddylation PMID:15966899
enablesGO:0005515 protein binding with PR:Q13616-1 PMID:11027288
GO:0005515 protein binding with PR:Q9EQW6 mOLIG2 PMID:11027288
located_inGO:0000151 ubiquitin ligase complex PMID:17217622
GO:0000151 ubiquitin ligase complex PMID:17217622
GO:0019005 SCF ubiquitin ligase complex PMID:15966899
GO:0031462 Cul2-RING ubiquitin ligase complex PMID:15966899