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Protein Ontology report - pituitary homeobox 2 (mouse)
PR:P97474 -
http://purl.obolibrary.org/obo/PR_P97474
Protein Forms
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:P97474
PRO name
pituitary homeobox 2 (mouse)
Synonyms
PRO-Short-label
:
EXACT:
mPITX2
Gene-based
:
RELATED:
Arp1 | Brx1 | Otlx2 | Pitx2 | Ptx2 | Rgs | Rieg
Other
:
EXACT:
ALL1-responsive protein ARP1 (mouse) | bicoid-related homeobox protein 1 (mouse) | BRX1 homeoprotein (mouse) | homeobox protein PITX2 (mouse) | orthodenticle-like homeobox 2 (mouse) | paired-like homeodomain transcription factor 2 (mouse) | solurshin (mouse)
Definition
"A pituitary homeobox 2 that is encoded in the genome of mouse." [
OMA:P97474
, PRO:DNx]
PRO Category
organism-gene
Parent
PR:000000117
pituitary homeobox 2
PR:000029032
Mus musculus protein
Gene Template
MGI:109340
Pitx2 (mouse)
Taxon
NCBITaxon:10090
Mus musculus
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
0
Organism-Gene
1
Sequence
0
Organism-Sequence
6
Modification
0
Organism-Modification
0
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
UniProtKB:P97474
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Protein Forms
Switch to
Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
organism-gene
PR:P97474
pituitary homeobox 2 (mouse)
mPITX2
"A pituitary homeobox 2 that is encoded in the genome of mouse." [OMA:P97474, PRO:DNx]
organism-sequence
PR:000036295
pituitary homeobox 2 isoform 4 (mouse)
mPITX2/iso:4
"A pituitary homeobox 2 isoform 4 that is encoded in the genome of mouse." [PMID:11948188, PRO:DAN]
organism-sequence
PR:P97474-1
pituitary homeobox 2 isoform Ptx2B (mouse)
mPITX2/iso:Ptx2B
"A pituitary homeobox 2 isoform Ptx2B that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P97474]
Yes
organism-sequence
PR:P97474-2
pituitary homeobox 2 isoform Ptx2C (mouse)
mPITX2/iso:Ptx2C
"A pituitary homeobox 2 isoform Ptx2C that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P97474]
Yes
organism-sequence
PR:P97474-3
pituitary homeobox 2 isoform Ptx2A (mouse)
mPITX2/iso:Ptx2A
"A pituitary homeobox 2 isoform Ptx2A that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P97474]
Yes
organism-sequence
PR:P97474-4
pituitary homeobox 2 isoform Ptx2Calpha (mouse)
mPITX2/iso:Ptx2Calpha
"A pituitary homeobox 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P97474-4." [PRO:DNx, UniProtKB:P97474]
organism-sequence
PR:P97474-5
pituitary homeobox 2 isoform Ptx2Cbeta (mouse)
mPITX2/iso:Ptx2Cbeta
"A pituitary homeobox 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P97474-5." [PRO:DNx, UniProtKB:P97474]
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:P97474-1
mPITX2/iso:Ptx2B
acts_upstream_of_or_within
GO:0007368
determination of left/right symmetry
PMID:12397115
GO:0016055
Wnt signaling pathway
PMID:12464179
located_in
GO:0005667
transcription factor complex
PMID:12464179
;
PMID:15385555
PR:P97474-2
mPITX2/iso:Ptx2C
acts_upstream_of_or_within
GO:0007179
transforming growth factor beta receptor signaling pathway
PMID:10585561
GO:0007368
determination of left/right symmetry
PMID:9708732
GO:0007520
myoblast fusion
MGI_ref:3686567;
PMID:16958127
GO:0009887
animal organ morphogenesis
PMID:10585561
GO:2000288
positive regulation of myoblast proliferation
MGI_ref:3686567;
PMID:16958127
PR:P97474-3
mPITX2/iso:Ptx2A
acts_upstream_of_or_within
GO:0007266
Rho protein signal transduction
PMID:11854422
NOT
GO:0007368
determination of left/right symmetry
PMID:10585561
GO:0030036
actin cytoskeleton organization
PMID:11854422
GO:0043388
positive regulation of DNA binding
MGI_ref:3796777;
PMID:18458156
enables
GO:0000981
DNA-binding transcription factor activity, RNA polymerase II-specific
MGI_ref:3796777;
PMID:18458156
GO:0003677
DNA binding
MGI_ref:3796777;
PMID:18458156
GO:0003712
transcription coregulator activity
MGI_ref:3796777;
PMID:18458156
GO:0005515
protein binding
MGI_ref:3796777;
PMID:18458156
GO:0008134
transcription factor binding
PMID:15385555
located_in
GO:0005634
nucleus
PMID:11854422
GO:0005634
nucleus
PMID:11854422
