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Protein Ontology report - heat shock factor protein 1 (human)
PR:Q00613 - http://purl.obolibrary.org/obo/PR_Q00613
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q00613   
  PRO nameheat shock factor protein 1 (human) 
  Synonyms
PRO-Short-label: EXACT:hHSF1
Gene-based: RELATED:HSF1 | HSTF1
Other: EXACT:heat shock transcription factor 1 (human) | HSF 1 (human) | HSTF 1 (human)
  Definition"A heat shock factor protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q00613
  PRO Categoryorganism-gene 
  ParentPR:000008790 heat shock factor protein 1
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:5224 HSF1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q00613
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:Q00613

heat shock factor protein 1 (human)

hHSF1


"A heat shock factor protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q00613]


organism-sequence



PR:Q00613-1

heat shock factor protein 1 isoform Long (human)

hHSF1/iso:Long


"A heat shock factor protein 1 isoform Long that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000025723

heat shock factor protein 1 isoform Long phosphorylated 1 (human)

hHSF1/iso:Long/Phos:1


"A heat shock factor protein 1 isoform Long phosphorylated 1 in human. UniProtKB:Q00613-1, Ser-121, MOD:00046." [PMID:16278218, PRO:JAN]

Yes

organism-modification



PR:000025725

heat shock factor protein 1 isoform Long phosphorylated 2 (human)

hHSF1/iso:Long/Phos:2


"A heat shock factor protein 1 isoform Long phosphorylated 2 in human. UniProtKB:Q00613-1, Ser-303/Ser-307, MOD:00046." [PMID:12917326, PMID:9121459]

Yes

organism-sequence



PR:Q00613-2

heat shock factor protein 1 isoform Short (human)

hHSF1/iso:Short


"A heat shock factor protein 1 isoform Short that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000045863

heat shock factor protein 1 phosphorylated 1 (human)

hHSF1/Phos:1


"A heat shock factor protein 1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-142 of the amino acid sequence represented by UniProtKB:Q00613-1. Example: UniProtKB:Q00613-1, Thr-142, MOD:00047." [iPTMnet:Q00613, PMID:12659875]


organism-modification



PR:000047906

heat shock factor protein 1 phosphorylated 3 (human)

hHSF1/Phos:3


"A heat shock factor protein 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-303 of the amino acid sequence represented by UniProtKB:Q00613. UniProtKB:Q00613, Ser-303, MOD:00046." [PRO:DNx, Reactome:R-HSA-4793927]


organism-modification



PR:000047907

heat shock factor protein 1 phosphorylated 2 (human)

hHSF1/Phos:2


"A heat shock factor protein 1 (human) that has been post-translationally modified to include phosphoserine at positions 303 and 307 of the amino acid sequence represented by UniProtKB:Q00613. UniProtKB:Q00613, Ser-303/Ser-307, MOD:00046." [PRO:DNx, Reactome:R-HSA-4793922]


organism-modification



PR:000047908

heat shock factor protein 1 phosphorylated 4 (human)

hHSF1/Phos:4


"A heat shock factor protein 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-307 of the amino acid sequence represented by UniProtKB:Q00613. UniProtKB:Q00613, Ser-307, MOD:00046." [PRO:DNx, Reactome:R-HSA-4793929]


organism-modification



PR:000063815

heat shock factor protein 1 phosphorylated 5 (human)

hHSF1/Phos:5


"A heat shock factor protein 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-121 of the amino acid sequence represented by UniProtKB:Q00613-1. Example: UniProtKB:Q00613-1, Ser-121, MOD:00046." [PRO:DNx, Reactome:R-HSA-4793906]


organism-modification



PR:000069043

heat shock factor protein 1 methylated 1 (human)

hHSF1/Me:1


"A heat shock factor protein 1 (human) that has been methylated on the residue at the position equivalent to Cys-378 of the amino acid sequence represented by UniProtKB:Q00613-1. Example: UniProtKB:Q00613-1, Cys-378, MOD:00660." [IEDB_epitope:1056412, PRO:DNx]


organism-modification



PR:000085520

heat shock factor protein 1 methylated 2 (human)

hHSF1/Me:2


"A heat shock factor protein 1 (human) that has been methylated on the residue at the position equivalent to Cys-103 of the amino acid sequence represented by UniProtKB:Q00613-1. Example: UniProtKB:Q00613-1, Cys-103, MOD:00660." [IEDB_epitope:1053538, IEDB_epitope:1053539, PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000025723 hHSF1/iso:Long/Phos:1
UniProtKB:Q00613-1, Ser-121, MOD:00046
enablesNOT GO:0000976 transcription cis-regulatory region binding PMID:16278218
GO:0005515 protein binding with PR:P08238 heat shock 84 kDa (human) PMID:16278218
GO:0005515 protein binding PMID:16278218
PR:000025725 hHSF1/iso:Long/Phos:2
UniProtKB:Q00613-1, Ser-303/Ser-307, MOD:00046
enablesGO:0071889 14-3-3 protein binding with PR:P62258 14-3-3E (human) PMID:12917326
located_inGO:0005737 cytoplasm PMID:12917326