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Protein Ontology report - angiopoietin-1 receptor (human)
PR:Q02763 - http://purl.obolibrary.org/obo/PR_Q02763
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q02763   
  PRO nameangiopoietin-1 receptor (human) 
  Synonyms
PRO-Short-label: EXACT:hTEK
Gene-based: RELATED:TEK | TIE2 | VMCM | VMCM1
Other: EXACT:CD202b (human) | endothelial tyrosine kinase (human) | hTIE2 | p140 TEK (human) | tunica interna endothelial cell kinase (human) | tyrosine kinase with Ig and EGF homology domains-2 (human) | tyrosine-protein kinase receptor TEK (human) | tyrosine-protein kinase receptor TIE-2 (human)
  Definition"An angiopoietin-1 receptor that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q02763
  PRO Categoryorganism-gene 
  ParentPR:000002032 angiopoietin-1 receptor
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:11724 TEK (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 5                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q02763
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:Q02763

angiopoietin-1 receptor (human)

hTEK


"An angiopoietin-1 receptor that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q02763]


organism-sequence



PR:000002131

angiopoietin-1 receptor sequence variant R849W (human)

hTEK/var:R849W


"An angiopoietin-1 receptor (human) that has a Trp residue at the position equivalent to Arg-849 of the amino acid sequence represented by UniProtKB:Q02763-1. Example: UniProtKB:Q02763-1, Arg-849, CHEBI:29954." [PMID:10369874, PMID:8980225, PMID:99199243, PRO:CNA, PRO:DAN]

Yes

organism-sequence



PR:000002132

angiopoietin-1 receptor sequence variant Y897S (human)

hTEK/var:Y897S


"An angiopoietin-1 receptor (human) that has a Ser residue at the position equivalent to Tyr-897 of the amino acid sequence represented by UniProtKB:Q02763-1. Example: UniProtKB:Q02763-1, Tyr-897, CHEBI:29999." [PMID:10369874, PRO:CNA, PRO:DAN]

Yes

organism-sequence



PR:Q02763-1

angiopoietin-1 receptor isoform 1 (human)

hTEK/iso:1


"An angiopoietin-1 receptor isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q02763-2

angiopoietin-1 receptor isoform h2 (human)

hTEK/iso:h2


"An angiopoietin-1 receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02763-2." [PRO:DNx, UniProtKB:Q02763]


organism-sequence



PR:Q02763-3

angiopoietin-1 receptor isoform h3 (human)

hTEK/iso:h3


"An angiopoietin-1 receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02763-3." [PRO:DNx, UniProtKB:Q02763]


organism-modification



PR:000049418

angiopoietin-1 receptor, signal peptide removed form (human)

hTEK/SigPep-


"An angiopoietin-1 receptor (human) that has had the signal peptide removed. UniProtKB:Q02763, 23-1124." [PRO:DNx, Reactome:R-HSA-197755]


organism-modification



PR:000049419

angiopoietin-1 receptor, signal peptide removed phosphorylated 1 (human)

hTEK/SigPep-/Phos:1


"An angiopoietin-1 receptor (human) that has had the signal peptide removed and has been post-translationally modified to include phosphotyrosine at positions 816, 992, 1102, 1108 and 1113, and phosphoserine at position 1119 of the amino acid sequence represented by UniProtKB:Q02763. UniProtKB:Q02763, 23-1124, Tyr-816/Tyr-992/Tyr-1102/Tyr-1108/Tyr-1113, MOD:00048|Ser-1119, MOD:00046." [PRO:DNx, Reactome:R-HSA-204772]


organism-modification



PR:000056851

angiopoietin-1 receptor N-glycosylated 1 (human)

hTEK/NGlyco:1


"An angiopoietin-1 receptor (human) that has been N-glycosylated at the residue equivalent to Asn-649 of the amino acid sequence represented by UniProtKB:Q02763-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:Q02763-1, Asn-649, MOD:00160~GNO:G58001LT." [GlyGen:Q02763-1, PMID:23345538, PRO:DNx]


organism-modification



PR:000081311

angiopoietin-1 receptor deaminated 1 (human)

hTEK/Deam:1


"An angiopoietin-1 receptor (human) that has been deaminated on the residue at the position equivalent to Asn-975 of the amino acid sequence represented by UniProtKB:Q02763-1. Example: UniProtKB:Q02763-1, Asn-975, MOD:00684." [IEDB_epitope:1990091, PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000002131 hTEK/var:R849W
Example: UniProtKB:Q02763-1, Arg-849, CHEBI:29954
associated_with_disease_progressionDO:0050792 multiple cutaneous and mucosal venous malformations PMID:10369874; PMID:8980225
enablesGO:0005515 protein binding with PR:P27986-1 PMID:10369874
PR:000002132 hTEK/var:Y897S
Example: UniProtKB:Q02763-1, Tyr-897, CHEBI:29999
associated_with_disease_progressionDO:0050792 multiple cutaneous and mucosal venous malformations PMID:10369874
enablesGO:0005515 protein binding with PR:P27986-1 PMID:10369874