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Protein Ontology report - serine/threonine-protein kinase PAK 1 (human)
PR:Q13153 - http://purl.obolibrary.org/obo/PR_Q13153
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q13153   
  PRO nameserine/threonine-protein kinase PAK 1 (human) 
  Synonyms
PRO-Short-label: EXACT:hPAK1
Gene-based: RELATED:PAK1
Other: EXACT:alpha-PAK (human) | p21-activated kinase 1 (human) | p65-PAK (human)
  Definition"A serine/threonine-protein kinase PAK 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13153
  PRO Categoryorganism-gene 
  ParentPR:000012239 serine/threonine-protein kinase PAK 1
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:8590 PAK1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q13153
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:Q13153

serine/threonine-protein kinase PAK 1 (human)

hPAK1


"A serine/threonine-protein kinase PAK 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13153]


organism-sequence



PR:Q13153-1

serine/threonine-protein kinase PAK 1 isoform 1 (human)

hPAK1/iso:1


"A serine/threonine-protein kinase PAK 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13153-1." [PRO:DNx, UniProtKB:Q13153]


organism-sequence



PR:Q13153-2

serine/threonine-protein kinase PAK 1 isoform h2 (human)

hPAK1/iso:h2


"A serine/threonine-protein kinase PAK 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13153-2." [PRO:DNx, UniProtKB:Q13153]


organism-modification



PR:000035776

serine/threonine-protein kinase PAK 1 phosphorylated 1 (human)

hPAK1/Phos:1


"A serine/threonine-protein kinase PAK 1 phosphorylated 1 in human. UniProtKB:Q13153, Thr-423, MOD:00047." [PMID:22369945, PRO:IC]

Yes

organism-modification



PR:000045900

serine/threonine-protein kinase PAK 1 phosphorylated 2 (human)

hPAK1/Phos:2


"A serine/threonine-protein kinase PAK 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-174 of the amino acid sequence represented by UniProtKB:Q13153-1. Example: UniProtKB:Q13153-1, Ser-174, MOD:00046." [iPTMnet:Q13153, PMID:19520772]


organism-modification



PR:000048687

serine/threonine-protein kinase PAK 1 phosphorylated 3 (human)

hPAK1/Phos:3


"A serine/threonine-protein kinase PAK 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-144 of the amino acid sequence represented by UniProtKB:Q13153. UniProtKB:Q13153, Ser-144, MOD:00046." [PRO:DNx]


organism-modification



PR:000048688

serine/threonine-protein kinase PAK 1 phosphorylated 4 (human)

hPAK1/Phos:4


"A serine/threonine-protein kinase PAK 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-144, and phosphothreonine at position 423 of the amino acid sequence represented by UniProtKB:Q13153. UniProtKB:Q13153, Ser-144, MOD:00046|Thr-423, MOD:00047." [PRO:DNx, Reactome:R-HSA-3928472, Reactome:R-HSA-399819]


organism-modification



PR:000084152

serine/threonine-protein kinase PAK 1 methylated 1 (human)

hPAK1/Me:1


"A serine/threonine-protein kinase PAK 1 (human) that has been methylated on the residue at the position equivalent to Cys-373 of the amino acid sequence represented by UniProtKB:Q13153-1. Example: UniProtKB:Q13153-1, Cys-373, MOD:00660." [IEDB_epitope:1040718, PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035776 hPAK1/Phos:1
UniProtKB:Q13153, Thr-423, MOD:00047
enablesGO:0004674 protein serine/threonine kinase activity PMID:22369945
GO:0008013 beta-catenin binding PMID:22369945