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Protein Ontology report - bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (human)
PR:Q14191 -
http://purl.obolibrary.org/obo/PR_Q14191
Protein Forms
Ontology Information
Show OBO stanza
/
GPI
PRO ID
PR:Q14191
PRO name
bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (human)
Synonyms
PRO-Short-label
:
EXACT:
hWRN
Gene-based
:
RELATED:
RECQ3 | RECQL2 | WRN
Other
:
EXACT:
DNA helicase, RecQ-like type 3 (human) | RecQ protein-like 2 (human) | Werner syndrome protein (human)
Definition
"A bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN that is encoded in the genome of human." [PRO:DNx,
UniProtKB:Q14191
]
PRO Category
organism-gene
Parent
PR:000017455
bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN
PR:000029067
Homo sapiens protein
Gene Template
HGNC:12791
WRN (human)
Taxon
NCBITaxon:9606
Homo sapiens
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
0
Organism-Gene
1
Sequence
0
Organism-Sequence
0
Modification
0
Organism-Modification
3
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
UniProtKB:Q14191
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Protein Forms
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Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
organism-gene
PR:Q14191
bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (human)
hWRN
"A bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q14191]
organism-modification
PR:000049701
bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN sumoylated 1 (human)
hWRN/Sumo:1
"A bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (human) that has been post-translationally modified to include sumoylated lysine at positions 356, 496 and 898 of the amino acid sequence represented by UniProtKB:Q14191. UniProtKB:Q14191, Lys-356/Lys-496/Lys-898, MOD:01149." [PRO:DNx, Reactome:R-HSA-4568904]
organism-modification
PR:000078581
bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN phosphorylated 1 (human)
hWRN/Phos:1
"A bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (human) that has been phosphorylated on the residue at the position equivalent to Thr-1236 of the amino acid sequence represented by UniProtKB:Q14191. UniProtKB:Q14191, Thr-1236, MOD:00047." [IEDB_epitope:2146027, PRO:DNx]
organism-modification
PR:000079912
bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN phosphorylated 2 (human)
hWRN/Phos:2
"A bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (human) that has been phosphorylated on the residue at the position equivalent to Ser-1279 of the amino acid sequence represented by UniProtKB:Q14191. UniProtKB:Q14191, Ser-1279, MOD:00046." [IEDB_epitope:2148980, PRO:DNx]