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Protein Ontology report - bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (human)
PR:Q14191 - http://purl.obolibrary.org/obo/PR_Q14191
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q14191   
  PRO namebifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (human) 
  Synonyms
PRO-Short-label: EXACT:hWRN
Gene-based: RELATED:RECQ3 | RECQL2 | WRN
Other: EXACT:DNA helicase, RecQ-like type 3 (human) | RecQ protein-like 2 (human) | Werner syndrome protein (human)
  Definition"A bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q14191
  PRO Categoryorganism-gene 
  ParentPR:000017455 bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:12791 WRN (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q14191
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:Q14191

bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (human)

hWRN


"A bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q14191]


organism-modification



PR:000049701

bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN sumoylated 1 (human)

hWRN/Sumo:1


"A bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (human) that has been post-translationally modified to include sumoylated lysine at positions 356, 496 and 898 of the amino acid sequence represented by UniProtKB:Q14191. UniProtKB:Q14191, Lys-356/Lys-496/Lys-898, MOD:01149." [PRO:DNx, Reactome:R-HSA-4568904]


organism-modification



PR:000078581

bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN phosphorylated 1 (human)

hWRN/Phos:1


"A bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (human) that has been phosphorylated on the residue at the position equivalent to Thr-1236 of the amino acid sequence represented by UniProtKB:Q14191. UniProtKB:Q14191, Thr-1236, MOD:00047." [IEDB_epitope:2146027, PRO:DNx]


organism-modification



PR:000079912

bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN phosphorylated 2 (human)

hWRN/Phos:2


"A bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (human) that has been phosphorylated on the residue at the position equivalent to Ser-1279 of the amino acid sequence represented by UniProtKB:Q14191. UniProtKB:Q14191, Ser-1279, MOD:00046." [IEDB_epitope:2148980, PRO:DNx]