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Protein Ontology report - mitogen-activated protein kinase 14 (human)
PR:Q16539 - http://purl.obolibrary.org/obo/PR_Q16539
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q16539   
  PRO namemitogen-activated protein kinase 14 (human) 
  Synonyms
PRO-Short-label: EXACT:hMAPK14
Gene-based: RELATED:CSBP | CSBP1 | CSBP2 | CSPB1 | MAPK14 | MXI2 | SAPK2A
Other: EXACT:CSAID-binding protein (human) | cytokine suppressive anti-inflammatory drug-binding protein (human) | MAP kinase 14 (human) | MAP kinase MXI2 (human) | MAP kinase p38 alpha (human) | MAPK 14 (human) | MAX-interacting protein 2 (human) | mitogen-activated protein kinase p38 alpha (human) | stress-activated protein kinase 2a (human)
  Definition"A mitogen-activated protein kinase 14 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q16539
  PRO Categoryorganism-gene 
  ParentPR:000003107 mitogen-activated protein kinase 14
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:6876 MAPK14 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 5                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q16539
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:Q16539

mitogen-activated protein kinase 14 (human)

hMAPK14


"A mitogen-activated protein kinase 14 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q16539]


organism-sequence



PR:Q16539-1

mitogen-activated protein kinase 14 isoform CSBP2 (human)

hMAPK14/iso:CSBP2


"A mitogen-activated protein kinase 14 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q16539-2

mitogen-activated protein kinase 14 isoform CSBP1 (human)

hMAPK14/iso:CSBP1


"A mitogen-activated protein kinase 14 isoform 2 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q16539-3

mitogen-activated protein kinase 14 isoform hMxi2 (human)

hMAPK14/iso:hMxi2


"A mitogen-activated protein kinase 14 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16539-3." [PRO:DNx, UniProtKB:Q16539]


organism-sequence



PR:Q16539-4

mitogen-activated protein kinase 14 isoform Exip (human)

hMAPK14/iso:Exip


"A mitogen-activated protein kinase 14 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16539-4." [PRO:DNx, UniProtKB:Q16539]


organism-sequence



PR:Q16539-5

mitogen-activated protein kinase 14 isoform h5 (human)

hMAPK14/iso:h5


"A mitogen-activated protein kinase 14 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16539-5." [PRO:DNx, UniProtKB:Q16539]


organism-modification



PR:000036637

mitogen-activated protein kinase 14 phosphorylated 1 (human)

hMAPK14/Phos:1


"A mitogen-activated protein kinase 14 phosphorylated 1 in human. Example: UniProtKB:Q16539-1, Thr-180, MOD:00047|Tyr-182, MOD:00048." [PMID:15642743, PRO:CL]

Yes

organism-modification



PR:000048319

mitogen-activated protein kinase 14, initiator methionine removed form (human)

hMAPK14/InitMet-


"A mitogen-activated protein kinase 14 (human) that has had the initiator methionine removed. UniProtKB:Q16539, 2-360." [PRO:DNx, Reactome:R-HSA-428933, Reactome:R-HSA-446223]


organism-modification



PR:000048320

mitogen-activated protein kinase 14, initiator methionine removed phosphorylated 1 (human)

hMAPK14/InitMet-/Phos:1


"A mitogen-activated protein kinase 14 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 180, and phosphotyrosine at position 182 of the amino acid sequence represented by UniProtKB:Q16539. UniProtKB:Q16539, 2-360, Thr-180, MOD:00047|Tyr-182, MOD:00048." [PRO:DNx, Reactome:R-HSA-428935, Reactome:R-HSA-446227]


organism-modification



PR:000067949

mitogen-activated protein kinase 14 deaminated 1 (human)

hMAPK14/Deam:1


"A mitogen-activated protein kinase 14 (human) that has been deaminated on the residue at the position equivalent to Gln-325 of the amino acid sequence represented by UniProtKB:Q16539-1. Example: UniProtKB:Q16539-1, Gln-325, MOD:00685." [IEDB_epitope:1976216, PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036637 hMAPK14/Phos:1
Example: UniProtKB:Q16539-1, Thr-180, MOD:00047|Tyr-182, MOD:00048
acts_upstream_of_or_withinGO:0006915 apoptotic process PMID:15642743
enablesGO:0004707 MAP kinase activity PMID:15642743
GO:0005515 protein binding PMID:15642743