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Protein Ontology report - hypoxia-inducible factor 1-alpha (human)
PR:Q16665 - http://purl.obolibrary.org/obo/PR_Q16665
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q16665   
  PRO namehypoxia-inducible factor 1-alpha (human) 
  Synonyms
PRO-Short-label: EXACT:hHIF1A
Gene-based: RELATED:BHLHE78 | HIF1A | MOP1 | PASD8
Other: EXACT:ARNT-interacting protein (human) | basic-helix-loop-helix-PAS protein MOP1 (human) | class E basic helix-loop-helix protein 78 (human) | HIF-1-alpha (human) | HIF1-alpha (human) | member of PAS protein 1 (human) | PAS domain-containing protein 8 (human)
  Definition"A hypoxia-inducible factor 1-alpha that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q16665
  PRO Categoryorganism-gene 
  ParentPR:000008555 hypoxia-inducible factor 1-alpha
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:4910 HIF1A (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 16                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q16665
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:Q16665

hypoxia-inducible factor 1-alpha (human)

hHIF1A


"A hypoxia-inducible factor 1-alpha that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q16665]


organism-sequence



PR:Q16665-1

hypoxia-inducible factor 1-alpha isoform 1 (human)

hHIF1A/iso:1


"A hypoxia-inducible factor 1-alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16665-1." [PRO:DNx, UniProtKB:Q16665]


organism-sequence



PR:Q16665-2

hypoxia-inducible factor 1-alpha isoform h2 (human)

hHIF1A/iso:h2


"A hypoxia-inducible factor 1-alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16665-2." [PRO:DNx, UniProtKB:Q16665]


organism-sequence



PR:Q16665-3

hypoxia-inducible factor 1-alpha isoform h3 (human)

hHIF1A/iso:h3


"A hypoxia-inducible factor 1-alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16665-3." [PRO:DNx, UniProtKB:Q16665]


organism-modification



PR:000045960

hypoxia-inducible factor 1-alpha phosphorylated 1 (human)

hHIF1A/Phos:1


"A hypoxia-inducible factor 1-alpha (human) that has been phosphorylated on the residue at the position equivalent to Ser-247 of the amino acid sequence represented by UniProtKB:Q16665-1. Example: UniProtKB:Q16665-1, Ser-247, MOD:00046." [iPTMnet:Q16665, PMID:20699359]


organism-modification



PR:000047696

hypoxia-inducible factor 1-alpha phosphorylated 2 (human)

hHIF1A/Phos:2


"A hypoxia-inducible factor 1-alpha (human) that has been phosphorylated on the residue at the position equivalent to Tyr-565, and phosphoserine at position 797 of the amino acid sequence represented by UniProtKB:Q16665. UniProtKB:Q16665, Tyr-565, MOD:00048|Ser-797, MOD:00046." [PRO:DNx, Reactome:R-HSA-9634700]


organism-modification



PR:000060469

hypoxia-inducible factor 1-alpha hydroxylated 1 (human)

hHIF1A/Hy:1


"A hypoxia-inducible factor 1-alpha (human) that has been hydroxylated on the residues at the positions equivalent to Pro-402 and Pro-564 of the amino acid sequence represented by UniProtKB:Q16665-1. Example: UniProtKB:Q16665-1, Pro-402/Pro-564, MOD:01024." [PRO:DNx, Reactome:R-HSA-1234105, Reactome:R-HSA-1234131]


organism-modification



PR:000060660

hypoxia-inducible factor 1-alpha hydroxylated 2 (human)

hHIF1A/Hy:2


"A hypoxia-inducible factor 1-alpha (human) that has been hydroxylated on the residue at the position equivalent to Asn-803 of the amino acid sequence represented by UniProtKB:Q16665-1. Example: UniProtKB:Q16665-1, Asn-803, MOD:01688." [PRO:DNx, Reactome:R-HSA-1234110]


organism-modification



PR:000064206

hypoxia-inducible factor 1-alpha phosphorylated 3 (human)

hHIF1A/Phos:3


"A hypoxia-inducible factor 1-alpha (human) that has been phosphorylated on the residue at the position equivalent to Tyr-565 of the amino acid sequence represented by UniProtKB:Q16665-1. Example: UniProtKB:Q16665-1, Tyr-565, MOD:00048." [PRO:DNx, Reactome:R-HSA-8857584]


organism-modification



PR:000064893

hypoxia-inducible factor 1-alpha phosphorylated 4 (human)

hHIF1A/Phos:4


"A hypoxia-inducible factor 1-alpha (human) that has been phosphorylated on the residue at the position equivalent to Ser-687 of the amino acid sequence represented by UniProtKB:Q16665-1. Example: UniProtKB:Q16665-1, Ser-687, MOD:00046." [IEDB_epitope:608786, IEDB_epitope:608787, PRO:DNx]


organism-modification



PR:000065188

hypoxia-inducible factor 1-alpha phosphorylated 5 (human)

hHIF1A/Phos:5


"A hypoxia-inducible factor 1-alpha (human) that has been phosphorylated on the residue at the position equivalent to Ser-668 of the amino acid sequence represented by UniProtKB:Q16665-1. Example: UniProtKB:Q16665-1, Ser-668, MOD:00046." [IEDB_epitope:848535, PRO:DNx]


organism-modification



PR:000065290

hypoxia-inducible factor 1-alpha methylated 1 (human)

hHIF1A/Me:1


"A hypoxia-inducible factor 1-alpha (human) that has been methylated on the residue at the position equivalent to Cys-173 of the amino acid sequence represented by UniProtKB:Q16665-1. Example: UniProtKB:Q16665-1, Cys-173, MOD:00660." [IEDB_epitope:1011565, PRO:DNx]


organism-modification



PR:000066553

hypoxia-inducible factor 1-alpha methylated 2 (human)

hHIF1A/Me:2


"A hypoxia-inducible factor 1-alpha (human) that has been methylated on the residue at the position equivalent to Cys-780 of the amino acid sequence represented by UniProtKB:Q16665-1. Example: UniProtKB:Q16665-1, Cys-780, MOD:00660." [IEDB_epitope:1021709, PRO:DNx]


organism-modification



PR:000067218

hypoxia-inducible factor 1-alpha methylated 3 (human)

hHIF1A/Me:3


"A hypoxia-inducible factor 1-alpha (human) that has been methylated on the residue at the position equivalent to Cys-255 of the amino acid sequence represented by UniProtKB:Q16665-1. Example: UniProtKB:Q16665-1, Cys-255, MOD:00660." [IEDB_epitope:1060791, PRO:DNx]


organism-modification



PR:000069219

hypoxia-inducible factor 1-alpha deaminated 1 (human)

hHIF1A/Deam:1


"A hypoxia-inducible factor 1-alpha (human) that has been deaminated on the residue at the position equivalent to Gln-87 of the amino acid sequence represented by UniProtKB:Q16665-1. Example: UniProtKB:Q16665-1, Gln-87, MOD:00685." [IEDB_epitope:1982870, PRO:DNx]


organism-modification



PR:000070222

hypoxia-inducible factor 1-alpha cysteinylated 1 (human)

hHIF1A/Cyst:1


"A hypoxia-inducible factor 1-alpha (human) that has been cysteinylated on the residue at the position equivalent to Cys-90 of the amino acid sequence represented by UniProtKB:Q16665-1. Example: UniProtKB:Q16665-1, Cys-90, MOD:00765." [IEDB_epitope:1565061, PRO:DNx]


organism-modification



PR:000071744

hypoxia-inducible factor 1-alpha cysteinylated 2 (human)

hHIF1A/Cyst:2


"A hypoxia-inducible factor 1-alpha (human) that has been cysteinylated on the residue at the position equivalent to Cys-173 of the amino acid sequence represented by UniProtKB:Q16665-1. Example: UniProtKB:Q16665-1, Cys-173, MOD:00765." [IEDB_epitope:1011564, PRO:DNx]


organism-modification



PR:000076874

hypoxia-inducible factor 1-alpha cysteinylated 3 (human)

hHIF1A/Cyst:3


"A hypoxia-inducible factor 1-alpha (human) that has been cysteinylated on the residue at the position equivalent to Cys-194 of the amino acid sequence represented by UniProtKB:Q16665-1. Example: UniProtKB:Q16665-1, Cys-194, MOD:00765." [IEDB_epitope:1017393, PRO:DNx]


organism-modification



PR:000081031

hypoxia-inducible factor 1-alpha methylated 4 (human)

hHIF1A/Me:4


"A hypoxia-inducible factor 1-alpha (human) that has been methylated on the residue at the position equivalent to Cys-219 of the amino acid sequence represented by UniProtKB:Q16665-1. Example: UniProtKB:Q16665-1, Cys-219, MOD:00660." [IEDB_epitope:1061528, PRO:DNx]


organism-modification



PR:000083569

hypoxia-inducible factor 1-alpha cysteinylated 4 (human)

hHIF1A/Cyst:4


"A hypoxia-inducible factor 1-alpha (human) that has been cysteinylated on the residue at the position equivalent to Cys-255 of the amino acid sequence represented by UniProtKB:Q16665-1. Example: UniProtKB:Q16665-1, Cys-255, MOD:00765." [IEDB_epitope:1060790, PRO:DNx]