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Protein Ontology report - Bcl2-associated agonist of cell death (mouse)
PR:Q61337 - http://purl.obolibrary.org/obo/PR_Q61337
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q61337   
  PRO nameBcl2-associated agonist of cell death (mouse) 
  Synonyms
PRO-Short-label: EXACT:mBAD
Gene-based: RELATED:Bad | Bbc6
Other: EXACT:BAD (mouse) | Bcl-2-binding component 6 (mouse) | Bcl-xL/Bcl-2-associated death promoter (mouse) | Bcl2 antagonist of cell death (mouse)
  Definition"A Bcl2-associated agonist of cell death that is encoded in the genome of mouse." [OMA:Q61337, PRO:DNx] 
  PRO Categoryorganism-gene 
  ParentPR:000002184 Bcl2-associated agonist of cell death
PR:000029032 Mus musculus protein
  Gene TemplateMGI:1096330 Bad (mouse)
  TaxonNCBITaxon:10090 Mus musculus
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q61337
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:Q61337

Bcl2-associated agonist of cell death (mouse)

mBAD


"A Bcl2-associated agonist of cell death that is encoded in the genome of mouse." [OMA:Q61337, PRO:DNx]


organism-sequence



PR:Q3U9H3

Bcl2-associated agonist of cell death isoform 2 (mouse)

mBAD/iso:2


"A Bcl2-associated agonist of cell death isoform 2 that is encoded in the genome of mouse." [PRO:JAN]


organism-sequence



PR:Q61337-1

Bcl2-associated agonist of cell death isoform 1 (mouse)

mBAD/iso:1


"A Bcl2-associated agonist of cell death isoform 1 that is encoded in the genome of mouse." [PRO:JAN]


organism-modification



PR:000026133

Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 (mouse)

mBAD/iso:1/Phos:2


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 in mouse. UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046." [PMID:10880354, PMID:10949026, PRO:JAN]

Yes

organism-modification



PR:000026135

Bcl2-associated agonist of cell death isoform 1 phosphorylated 4 (mouse)

mBAD/iso:1/Phos:4


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 4 in mouse. UniProtKB:Q61337-1, Thr-201, MOD:00047." [PMID:14967141, PRO:JAN]

Yes

organism-modification



PR:000026136

Bcl2-associated agonist of cell death isoform 1 phosphorylated 5 (mouse)

mBAD/iso:1/Phos:5


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 5 in mouse. UniProtKB:Q61337-1, Ser-136, MOD:00046." [PMID:12049737, PRO:JAN]

Yes

organism-modification



PR:000026137

Bcl2-associated agonist of cell death isoform 1 phosphorylated 6 (mouse)

mBAD/iso:1/Phos:6


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 6 in mouse. UniProtKB:Q61337-1, Ser-128/Ser-136, MOD:00046." [PMID:12049737, PRO:JAN]

Yes

organism-modification



PR:000026138

Bcl2-associated agonist of cell death isoform 1 phosphorylated 7 (mouse)

mBAD/iso:1/Phos:7


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 7 in mouse. UniProtKB:Q61337-1, Ser-112/Ser-155, MOD:00046." [PMID:10880354, PRO:CNA]


organism-modification



PR:000026139

Bcl2-associated agonist of cell death isoform 1 phosphorylated 8 (mouse)

mBAD/iso:1/Phos:8


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 8 in mouse. UniProtKB:Q61337-1, Ser-155, MOD:00046." [PMID:10880354, PRO:CNA]

Yes

organism-modification



PR:000026167

Bcl2-associated agonist of cell death isoform 1 phosphorylated 1 (mouse)

mBAD/iso:1/Phos:1


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 1 in mouse. UniProtKB:Q61337-1, Ser-112/Ser-136, MOD:00046." [PMID:10949026, PMID:8929531, PMID:9346240, PRO:JAN]

Yes

organism-modification



PR:000037809

Bcl2-associated agonist of cell death isoform 1 unphosphorylated 1 (mouse)

mBAD/iso:1/UnPhos:1


"A Bcl2-associated agonist of cell death isoform 1 (mouse) that lacks phosphorylation on the indicated Ser residues located within each of two RxRxxSxP motifs, and the indicated Ser residue within the motif RRxS in the BH3 domain, which is the major PKA phosphorylation site. Example: UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, PR:000026291." [PMID:16403219, PRO:DAN, PRO:KER]


organism-modification



PR:000044747

Bcl2-associated agonist of cell death isoform 1 unmodified form (mouse)

mBAD/iso:1/UnMod


"A Bcl2-associated agonist of cell death isoform 1 unmodified form in mouse." [PRO:DNx]

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000026133 mBAD/iso:1/Phos:2
UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046
acts_upstream_of_or_withinGO:0043066 negative regulation of apoptotic process PMID:10949026
enablesNOT GO:0005515 protein binding with PR:000003237 fam:14-3-3 PMID:10949026
NOT GO:0005515 protein binding with PR:P63101-1 PMID:10949026
NOT GO:0005515 protein binding with PR:Q64373-1 PMID:10949026
NOT GO:0005515 protein binding with PR:Q07817-1 PMID:10949026
PR:000026135 mBAD/iso:1/Phos:4
UniProtKB:Q61337-1, Thr-201, MOD:00047
acts_upstream_of_or_withinGO:0043066 negative regulation of apoptotic process PMID:14967141
enablesdecreased GO:0005515 protein binding with PR:Q64373-1 PMID:14967141
PR:000026136 mBAD/iso:1/Phos:5
UniProtKB:Q61337-1, Ser-136, MOD:00046
enablesGO:0005515 protein binding with PR:P63101 KCIP-1 (mouse) PMID:12049737
PR:000026137 mBAD/iso:1/Phos:6
UniProtKB:Q61337-1, Ser-128/Ser-136, MOD:00046
acts_upstream_of_or_withinGO:0051402 neuron apoptotic process PMID:12049737
PR:000026139 mBAD/iso:1/Phos:8
UniProtKB:Q61337-1, Ser-155, MOD:00046
enablesGO:0071889 14-3-3 protein binding with PR:P61982 mYWHAG PMID:10880354
PR:000026167 mBAD/iso:1/Phos:1
UniProtKB:Q61337-1, Ser-112/Ser-136, MOD:00046
enablesdecreased GO:0005515 protein binding with PR:P62258-1 PMID:12049737
decreased GO:0005515 protein binding with PR:Q07817-1 PMID:12049737
decreased GO:0005515 protein binding with PR:Q9CQV8 KCIP-1 (mouse) PMID:12049737
decreased GO:0005515 protein binding with PR:P63101 KCIP-1 (mouse) PMID:12049737
PR:000044747 mBAD/iso:1/UnMod acts_upstream_of_or_withinGO:0006915 apoptotic process PMID:15280015
enablesGO:0005515 protein binding with PR:P04049 cRaf (human) PMID:17011751
GO:0005515 protein binding with PR:P06803-2 PMID:17011751
GO:0005515 protein binding with PR:P15056 BRAF PMID:17011751
GO:0005515 protein binding with PR:Q04759 hPRKCQ PMID:17011751
located_inGO:0031966 mitochondrial membrane PMID:15280015