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Protein Ontology report - outer kinetochore KNL1 complex subunit KNL1 (human)
PR:Q8NG31 - http://purl.obolibrary.org/obo/PR_Q8NG31
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:Q8NG31   
  PRO nameouter kinetochore KNL1 complex subunit KNL1 (human) 
  Synonyms
PRO-Short-label: EXACT:hKNL1
Gene-based: RELATED:CASC5 | KIAA1570 | KNL1
Other: EXACT:AF15q14 (human) | ALL1-fused gene from chromosome 15q14 protein (human) | blinkin (human) | Bub-linking kinetochore protein (human) | cancer susceptibility candidate gene 5 protein (human) | cancer/testis antigen 29 (human) | CT29 (human) | kinetochore scaffold 1 (human) | kinetochore-null protein 1 (human) | protein CASC5 (human) | protein D40/AF15q14 (human)
  Definition"An outer kinetochore KNL1 complex subunit KNL1 that is encoded in the genome of human." [PMID:20624902, PRO:KER] 
  PRO Categoryorganism-gene 
  ParentPR:000005050 outer kinetochore KNL1 complex subunit KNL1
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:24054 KNL1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q8NG31
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:Q8NG31 outer kinetochore KNL1 complex subunit KNL1 (human)
hKNL1
Yes
organism-sequence


PR:Q8NG31-1 outer kinetochore KNL1 complex subunit KNL1 isoform 1 (human)
hKNL1/iso:1

organism-sequence


PR:Q8NG31-2 outer kinetochore KNL1 complex subunit KNL1 isoform 2 (human)
hKNL1/iso:2

organism-modification


PR:000035558 outer kinetochore KNL1 complex subunit KNL1 isoform 2 phosphorylated 1 (human)
hKNL1/iso:2/Phos:1
Yes
organism-modification


PR:000035560 outer kinetochore KNL1 complex subunit KNL1 isoform 2 unphosphorylated form (human)
hKNL1/iso:2/PhosRes-

organism-sequence


PR:Q8NG31-3 outer kinetochore KNL1 complex subunit KNL1 isoform h3 (human)
hKNL1/iso:h3

organism-sequence


PR:Q8NG31-4 outer kinetochore KNL1 complex subunit KNL1 isoform h4 (human)
hKNL1/iso:h4

organism-modification


PR:000071007 outer kinetochore KNL1 complex subunit KNL1 methylated 1 (human)
hKNL1/Me:1

organism-modification


PR:000071490 outer kinetochore KNL1 complex subunit KNL1 cysteinylated 1 (human)
hKNL1/Cyst:1

organism-modification


PR:000077771 outer kinetochore KNL1 complex subunit KNL1 phosphorylated 1 (human)
hKNL1/Phos:1

organism-modification


PR:000083702 outer kinetochore KNL1 complex subunit KNL1 deaminated 1 (human)
hKNL1/Deam:1

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035558 hKNL1/iso:2/Phos:1
UniProtKB:Q8NG31-2, Thr-875/Thr-1075/Thr-1089/Thr-1129/Thr-1154/Thr-1167, MOD:00047|Ser-1022/Ser-1037, MOD:00046		 acts_upstream_of_or_withinincreased GO:0034501 protein localization to kinetochore relative to PR:000035560 hKNL1/iso:2/PhosRes- PMID:22660415
PR:Q8NG31 hKNL1 enablesGO:0005515 protein binding with PR:O14777 HEC BioGRID:BG-697221
GO:0005515 protein binding with PR:O43683 BUB1 BioGRID:BG-697221
GO:0005515 protein binding with PR:O60566 BUB1B BioGRID:BG-697221
located_inGO:0000776 kinetochore PMID:20624902