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Protein Ontology report - interferon regulatory factor 7 (human)
PR:Q92985 - http://purl.obolibrary.org/obo/PR_Q92985
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q92985   
  PRO nameinterferon regulatory factor 7 (human) 
  Synonyms
PRO-Short-label: EXACT:hIRF7
Gene-based: RELATED:IRF7
Other: EXACT:IRF-7 (human)
  Definition"An interferon regulatory factor 7 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q92985
  PRO Categoryorganism-gene 
  ParentPR:000002049 interferon regulatory factor 7
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:6122 IRF7 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q92985
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:Q92985

interferon regulatory factor 7 (human)

hIRF7


"An interferon regulatory factor 7 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q92985]


organism-sequence



PR:Q92985-1

interferon regulatory factor 7 isoform A (human)

hIRF7/iso:A


"An interferon regulatory factor 7 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000027082

interferon regulatory factor 7 isoform 1 phosphorylated 1 (human)

hIRF7/iso:1/Phos:1


"An interferon regulatory factor 7 isoform 1 phosphorylated 1 in human. UniProtKB:Q92985-1, Ser-477/Ser-479, MOD:00046." [PMID:10893229, PMID:14517278, TLR:AMM]


Yes
organism-modification



PR:000037791

interferon regulatory factor 7 isoform 1 unphosphorylated 1 (human)

hIRF7/iso:1/UnPhos:1


"An interferon regulatory factor 7 isoform 1 unphosphorylated 1 in human. UniProtKB:Q92985-1, Ser-477/Ser-479, PR:000026291." [PMID:10893229, PMID:14517278, PRO:CNA]

Yes

organism-sequence



PR:Q92985-2

interferon regulatory factor 7 isoform B (human)

hIRF7/iso:B


"An interferon regulatory factor 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92985-2." [PRO:DNx, UniProtKB:Q92985]


organism-sequence



PR:Q92985-3

interferon regulatory factor 7 isoform C (human)

hIRF7/iso:C


"An interferon regulatory factor 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92985-3." [PRO:DNx, UniProtKB:Q92985]


organism-sequence



PR:Q92985-4

interferon regulatory factor 7 isoform D (human)

hIRF7/iso:D


"An interferon regulatory factor 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92985-4." [PRO:DNx, UniProtKB:Q92985]


organism-modification



PR:000028704

interferon regulatory factor 7 unmodified form (human)

hIRF7/UnMod


"An interferon regulatory factor 7 unmodified form in human." [PRO:CNA]


Yes
organism-modification



PR:000048049

interferon regulatory factor 7 phosphorylated 1 (human)

hIRF7/Phos:1


"An interferon regulatory factor 7 (human) that has been post-translationally modified to include phosphoserine at positions 477 and 479 of the amino acid sequence represented by UniProtKB:Q92985. UniProtKB:Q92985, Ser-477/Ser-479, MOD:00046." [PRO:DNx, Reactome:R-HSA-450270, Reactome:R-HSA-450318]


organism-modification



PR:000048050

interferon regulatory factor 7 ubiquitinated form (human)

hIRF7/UbiqLys+


"An interferon regulatory factor 7 (human) that includes at least one ubiquitinated lysine. UniProtKB:Q92985, MOD:01148." [PRO:DNx, Reactome:R-HSA-975154]


organism-modification



PR:000066902

interferon regulatory factor 7 cysteinylated 1 (human)

hIRF7/Cyst:1


"An interferon regulatory factor 7 (human) that has been cysteinylated on the residue at the position equivalent to Cys-191 of the amino acid sequence represented by UniProtKB:Q92985-1. Example: UniProtKB:Q92985-1, Cys-191, MOD:00765." [IEDB_epitope:1336456, PRO:DNx]


organism-modification



PR:000078397

interferon regulatory factor 7 methylated 1 (human)

hIRF7/Me:1


"An interferon regulatory factor 7 (human) that has been methylated on the residue at the position equivalent to Cys-97 of the amino acid sequence represented by UniProtKB:Q92985-1. Example: UniProtKB:Q92985-1, Cys-97, MOD:00660." [IEDB_epitope:1027266, PRO:DNx]


organism-modification



PR:000080104

interferon regulatory factor 7 cysteinylated 2 (human)

hIRF7/Cyst:2


"An interferon regulatory factor 7 (human) that has been cysteinylated on the residue at the position equivalent to Cys-39 of the amino acid sequence represented by UniProtKB:Q92985-1. Example: UniProtKB:Q92985-1, Cys-39, MOD:00765." [IEDB_epitope:1593091, PRO:DNx]


organism-modification



PR:000080211

interferon regulatory factor 7 methylated 2 (human)

hIRF7/Me:2


"An interferon regulatory factor 7 (human) that has been methylated on the residue at the position equivalent to Cys-191 of the amino acid sequence represented by UniProtKB:Q92985-1. Example: UniProtKB:Q92985-1, Cys-191, MOD:00660." [IEDB_epitope:1039161, PRO:DNx]


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hIRF7 forms found in complexes   

hIRF7 Component
Complexes
PR:000027082 hIRF7/iso:1/Phos:1 PR:000027084 IRF3-P:IRF7-P complex (human)
PR:000027086 IRF7-P:IRF7-P complex (human)
PR:000028704 hIRF7/UnMod PR:000036034 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036038 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000037356 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000037360 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000037791 hIRF7/iso:1/UnPhos:1
UniProtKB:Q92985-1, Ser-477/Ser-479, PR:000026291
located_inGO:0005737 cytoplasm Reactome:REACT_21735