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Protein Ontology report - myeloid differentiation primary response protein MyD88 (human)
PR:Q99836 - http://purl.obolibrary.org/obo/PR_Q99836
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q99836   
  PRO namemyeloid differentiation primary response protein MyD88 (human) 
  Synonyms
PRO-Short-label: EXACT:hMYD88
Gene-based: RELATED:MYD88
  Definition"A myeloid differentiation primary response protein MyD88 that is encoded in the genome of human." [PRO:CNA] 
  PRO Categoryorganism-gene 
  ParentPR:000001740 myeloid differentiation primary response protein MyD88
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:7562 MYD88 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 9                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q99836
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:Q99836

myeloid differentiation primary response protein MyD88 (human)

hMYD88


"A myeloid differentiation primary response protein MyD88 that is encoded in the genome of human." [PRO:CNA]


Yes
organism-sequence



PR:000001742

myeloid differentiation primary response protein MyD88 sequence variant L93P (human)

hMYD88/var:L93P


"A myeloid differentiation primary response protein MyD88 (human) that has a Pro residue at the position equivalent to Leu-93 of the amino acid sequence represented by UniProtKB:Q99836-1. Example: UniProtKB:Q99836-1, Leu-93, CHEBI:50342." [PMID:18669862, PRO:CNA, PRO:DAN]


organism-sequence



PR:000001743

myeloid differentiation primary response protein MyD88 sequence variant R196C (human)

hMYD88/var:R196C


"A myeloid differentiation primary response protein MyD88 (human) that has a Cys residue at the position equivalent to Arg-196 of the amino acid sequence represented by UniProtKB:Q99836-1. Example: UniProtKB:Q99836-1, Arg-196, CHEBI:29950." [PMID:18669862, PRO:CNA, PRO:DAN]


organism-sequence



PR:000061325

myeloid differentiation primary response protein MyD88 sequence variant S34Y (human)

hMYD88/var:S34Y


"A myeloid differentiation primary response protein MyD88 (human) that has a Tyr residue at the position equivalent to Ser-34 of the amino acid sequence represented by UniProtKB:Q99836-1. Example: UniProtKB:Q99836-1, Ser-34, CHEBI:46858." [PRO:DNx, Reactome:R-HSA-5602521]


organism-sequence



PR:Q99836-1

myeloid differentiation primary response protein MyD88 isoform 1 (human)

hMYD88/iso:1


"A myeloid differentiation primary response protein MyD88 isoform 1 that is encoded in the genome of human." [PRO:CNA]


Yes
organism-sequence



PR:Q99836-2

myeloid differentiation primary response protein MyD88 isoform 2 (human)

hMYD88/iso:2


"A myeloid differentiation primary response protein MyD88 isoform 2 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q99836-3

myeloid differentiation primary response protein MyD88 isoform h3 (human)

hMYD88/iso:h3


"A myeloid differentiation primary response protein MyD88 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99836-3." [PRO:DNx, UniProtKB:Q99836]


organism-sequence



PR:Q99836-4

myeloid differentiation primary response protein MyD88 isoform h4 (human)

hMYD88/iso:h4


"A myeloid differentiation primary response protein MyD88 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99836-4." [PRO:DNx, UniProtKB:Q99836]


organism-sequence



PR:Q99836-5

myeloid differentiation primary response protein MyD88 isoform h5 (human)

hMYD88/iso:h5


"A myeloid differentiation primary response protein MyD88 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99836-5." [PRO:DNx, UniProtKB:Q99836]


organism-sequence



PR:Q99836-6

myeloid differentiation primary response protein MyD88 isoform h6 (human)

hMYD88/iso:h6


"A myeloid differentiation primary response protein MyD88 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99836-6." [PRO:DNx, UniProtKB:Q99836]


organism-modification



PR:000065926

myeloid differentiation primary response protein MyD88 methylated 1 (human)

hMYD88/Me:1


"A myeloid differentiation primary response protein MyD88 (human) that has been methylated on the residue at the position equivalent to Cys-233 of the amino acid sequence represented by UniProtKB:Q99836-1. Example: UniProtKB:Q99836-1, Cys-233, MOD:00660." [IEDB_epitope:1023386, PRO:DNx]


organism-modification



PR:000078147

myeloid differentiation primary response protein MyD88 cysteinylated 1 (human)

hMYD88/Cyst:1


"A myeloid differentiation primary response protein MyD88 (human) that has been cysteinylated on the residue at the position equivalent to Cys-280 of the amino acid sequence represented by UniProtKB:Q99836-1. Example: UniProtKB:Q99836-1, Cys-280, MOD:00765." [IEDB_epitope:933188, PRO:DNx]


organism-modification



PR:000082882

myeloid differentiation primary response protein MyD88 cysteinylated 2 (human)

hMYD88/Cyst:2


"A myeloid differentiation primary response protein MyD88 (human) that has been cysteinylated on the residue at the position equivalent to Cys-203 of the amino acid sequence represented by UniProtKB:Q99836-1. Example: UniProtKB:Q99836-1, Cys-203, MOD:00765." [IEDB_epitope:1331425, PRO:DNx]


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hMYD88 forms found in complexes   

hMYD88 Component
Complexes
PR:Q99836 hMYD88 PR:000037446 MYD88:TIRAP:PIP2:BTK:activated TLR4 complex (human)
PR:Q99836ZDASHZ1 hMYD88/iso:1 PR:000027183 IRAK4:MYD88:TIRAP:activated TLR4 complex (human)
PR:000027192 pIRAK4:MYD88:TIRAP:activated TLR4 complex (human)
PR:000027495 pIRAK1:pIRAK4:MYD88:TIRAP:activated TLR4 (human)