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Protein Ontology report - receptor-interacting serine/threonine-protein kinase 3 (human)
PR:Q9Y572 - http://purl.obolibrary.org/obo/PR_Q9Y572
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:Q9Y572   
  PRO namereceptor-interacting serine/threonine-protein kinase 3 (human) 
  Synonyms
PRO-Short-label: EXACT:hRIPK3
Gene-based: RELATED:RIP3 | RIPK3
Other: EXACT:receptor-interacting protein 3 (human) | RIP-3 (human) | RIP-like protein kinase 3 (human)
  Definition"A receptor-interacting serine/threonine-protein kinase 3 that is encoded in the genome of human." [PRO:CNA, Reactome:R-HSA-450328
  PRO Categoryorganism-gene 
  ParentPR:000014024 receptor-interacting serine/threonine-protein kinase 3
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:10021 RIPK3 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q9Y572
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:Q9Y572

receptor-interacting serine/threonine-protein kinase 3 (human)

hRIPK3


"A receptor-interacting serine/threonine-protein kinase 3 that is encoded in the genome of human." [PRO:CNA, Reactome:R-HSA-450328]

Yes

Yes
organism-sequence



PR:Q9Y572-1

receptor-interacting serine/threonine-protein kinase 3 isoform h1 (human)

hRIPK3/iso:h1


"A receptor-interacting serine/threonine-protein kinase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y572-1." [PRO:DNx, UniProtKB:Q9Y572]


organism-sequence



PR:Q9Y572-2

receptor-interacting serine/threonine-protein kinase 3 isoform h2 (human)

hRIPK3/iso:h2


"A receptor-interacting serine/threonine-protein kinase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y572-2." [PRO:DNx, UniProtKB:Q9Y572]


organism-sequence



PR:Q9Y572-3

receptor-interacting serine/threonine-protein kinase 3 isoform h3 (human)

hRIPK3/iso:h3


"A receptor-interacting serine/threonine-protein kinase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y572-3." [PRO:DNx, UniProtKB:Q9Y572]


organism-modification



PR:000049047

receptor-interacting serine/threonine-protein kinase 3 phosphorylated 1 (human)

hRIPK3/Phos:1


"A receptor-interacting serine/threonine-protein kinase 3 (human) that has been post-translationally modified to include phosphoserine at positions 199 and 227 of the amino acid sequence represented by UniProtKB:Q9Y572. UniProtKB:Q9Y572, Ser-199/Ser-227, MOD:00046." [PRO:DNx, Reactome:R-HSA-5218873]


organism-modification



PR:000064444

receptor-interacting serine/threonine-protein kinase 3 ubiquitinated 1 (human)

hRIPK3/Ubiq:1


"A receptor-interacting serine/threonine-protein kinase 3 (human) that has been ubiquitinated on the residues at the positions equivalent to Lys-55 and Lys-363 of the amino acid sequence represented by UniProtKB:Q9Y572-1. Example: UniProtKB:Q9Y572-1, Lys-55/Lys-363, MOD:01148." [PRO:DNx, Reactome:R-HSA-9688825]


organism-modification



PR:000064690

receptor-interacting serine/threonine-protein kinase 3 phosphorylated and ubiquitinated 1 (human)

hRIPK3/PhosUbiq:1


"A receptor-interacting serine/threonine-protein kinase 3 (human) that has been phosphorylated on the residues at the positions equivalent to Ser-199 and Ser-227 and ubiquitinated on the residue at the position equivalent to Lys-363 of the amino acid sequence represented by UniProtKB:Q9Y572-1. Example: UniProtKB:Q9Y572-1, Ser-199/Ser-227, MOD:00046|Lys-363, MOD:01148." [PRO:DNx, Reactome:R-HSA-9686933]


organism-modification



PR:000064837

receptor-interacting serine/threonine-protein kinase 3 ubiquitinated 2 (human)

hRIPK3/Ubiq:2


"A receptor-interacting serine/threonine-protein kinase 3 (human) that has been ubiquitinated on the residues at the positions equivalent to Lys-197, Lys-302, and Lys-364 of the amino acid sequence represented by UniProtKB:Q9Y572-1. Example: UniProtKB:Q9Y572-1, Lys-197/Lys-302/Lys-364, MOD:01148." [PRO:DNx, Reactome:R-HSA-9794180]


organism-modification



PR:000064845

receptor-interacting serine/threonine-protein kinase 3 O-glycosylated 1 (human)

hRIPK3/OGlyco:1


"A receptor-interacting serine/threonine-protein kinase 3 (human) that has been O-glycosylated on the residue at the position equivalent to Thr-467 of the amino acid sequence represented by UniProtKB:Q9Y572-1. Example: UniProtKB:Q9Y572-1, Thr-467, MOD:00005." [PRO:DNx, Reactome:R-HSA-9687819]


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hRIPK3 forms found in complexes   

hRIPK3 Component
Complexes
PR:Q9Y572 hRIPK3 PR:000036056 rip3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036058 rip1:rip3:ticam1:ticam2:activated TLR4 complex (human)
PR:000037332 rip3:ticam1:activated TLR3 complex (human)
PR:000037336 rip1:rip3:ticam1:activated TLR3 complex (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q9Y572 hRIPK3 located_inGO:0005737 cytoplasm Reactome:REACT_22021