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Protein Ontology report - smad2 isoform Long phosphorylated 1 (human)
PR:000025934 - http://purl.obolibrary.org/obo/PR_000025934
 
    Complex  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:000025934   
  PRO namesmad2 isoform Long phosphorylated 1 (human) 
  Synonyms
PRO-Short-label: EXACT:hSMAD2/iso:Long/Phos:1
PRO-proteoform-std: EXACT:UniProtKB:Q15796-1, Ser-465/Ser-467, MOD:00046
  Definition"A smad2 isoform Long phosphorylated 1 in human. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q15796-1, Ser-465/Ser-467, MOD:00046." [PMID:8980228, PMID:9346966
  CommentKinase=("TGFBR1"; PR:000025963; Ser-465/Ser-467). 
  PRO Categoryorganism-modification 
  ParentPR:000000650
PR:Q15796
  TaxonNCBITaxon:9606 Homo sapiens
  Term Hierarchy
  Visualization
DAG: OLS:
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hSMAD2/iso:Long/Phos:1 forms found in complexes   

hSMAD2/iso:Long/Phos:1 Component
Complexes
PR:000025934 hSMAD2/iso:Long/Phos:1 PR:000025933^P000025951
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term

Protein Forms & Complexes

Evidence
GO:0006355 regulation of DNA-templated transcriptionPR:000025934 hSMAD2/iso:Long/Phos:1 PMID:15690394; PMID:9689110
GO:0007165 signal transductionPR:000025934 hSMAD2/iso:Long/Phos:1 PMID:8752209; PMID:8980228; PMID:9346966
GO:0007179 transforming growth factor beta receptor signaling pathwayPR:000025934 hSMAD2/iso:Long/Phos:1 PMID:8752209; PMID:8980228
GO:0060395 SMAD protein signal transductionPR:000025934 hSMAD2/iso:Long/Phos:1 PMID:9346966

Molecular Function GO Term

Protein Forms & Complexes

Evidence
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specificPR:000025934 hSMAD2/iso:Long/Phos:1 PMID:8980228; PMID:9346966
GO:0003713 transcription coactivator activityPR:000025934 hSMAD2/iso:Long/Phos:1 PMID:9689110
GO:0046332 SMAD bindingPR:000025934 hSMAD2/iso:Long/Phos:1 PMID:9311995

Cellular Location GO Term

Protein Forms & Complexes

Evidence
GO:0005634 nucleusPR:000025934 hSMAD2/iso:Long/Phos:1 PMID:9006934; PMID:9346966