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PRO ID
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| PRO name | MYD88:TIRAP:PIP2:BTK:activated TLR4 complex (mouse) |
| Synonyms | | Other: | EXACT: | MyD88:MAL:PI(4,5)P2:BTK:activated TLR4 (mouse) | | RELATED: | MyD88:Mal complexed with the activated TLR (mouse) | |
| Definition | "A MYD88:TIRAP:PIP2:BTK:activated TLR4 complex in mouse that is composed of MyD88, PI(4,5)P2, TIRAP/MAL, BTK, TLR4, MD2, and LPS." [TLR:AMM] |
| Comment | Evidence=(ECO:0000088, based on PR:000037446). Note: CD14 has not been added as part of the complex because there is not supporting evidence in mouse that CD14 is in the activated TLR4 complexes, beyond the initial trasnfer of LPS. PMID:21441935 shows interaction of MYD88 with BTK. |
| PRO Category | organism-complex |
| Parent | PR:000037488 MYD88:TIRAP:PIP2:BTK:activated TLR4 complex
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| Taxon | NCBITaxon:10090 Mus musculus |
Term Hierarchy
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