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Protein Ontology report - IgA1 immunoglobulin complex (human)
PR:000050157 - http://purl.obolibrary.org/obo/PR_000050157
 
     
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:000050157   
  PRO nameIgA1 immunoglobulin complex (human) 
  Synonyms
PRO-Short-label: EXACT:hIgA1
Other: NARROW:IgA1 antibody (human)
  Definition"An IgA immunoglobulin complex in human that is composed of (in monomeric form) two identical immunoglobulin heavy chains of the IgA1 isotype and two identical immunoglobulin light chains (kappa or lambda) held together by disulfide bonds, and sometimes complexed with J chain or J chain and secretory component. An IgA1 immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, ISBN:0781765196, PMID:16362985, PRO:ADD] 
  CommentRequested by=HIPC. Requested by=CL. Note that an IgA1 immunoglobulin complex has the function of antigen binding if a suitable antigen is available. 
  PRO Categoryorganism-complex 
  ParentG0071745 IgA immunoglobulin complex
  TaxonNCBITaxon:9606 Homo sapiens
  Term Hierarchy
  Visualization
DAG: OLS: