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Protein Ontology report - potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
PR:000000705 - http://purl.obolibrary.org/obo/PR_000000705
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000705   
  PRO namepotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 
  Synonyms
PRO-Short-label: EXACT:HCN1
Gene-based: RELATED:BCNG1 | Hac2
Other: EXACT:BCNG-1 | brain cyclic nucleotide-gated channel 1 | HAC-2 | hyperpolarization-activated cation channel 2
  Definition"A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel protein that is a translation product of the human HCN1 gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000676 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 1                                        
         Modification2                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:400
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000000705 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
HCN1

organism-gene


PR:O60741 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (human)
hHCN1

organism-gene


PR:O88704 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (mouse)
mHCN1

organism-sequence


PR:O88704-1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 (mouse)
mHCN1/iso:1
Yes
organism-modification


PR:000036573 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 N-glycosylated 1 (mouse)
mHCN1/iso:1/NGlyco:1
Yes
organism-gene


PR:Q9JKB0 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (rat)
rHCN1

sequence


PR:000000755 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1
HCN1/iso:1

organism-sequence


PR:O88704-1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 (mouse)
mHCN1/iso:1
Yes
organism-modification


PR:000036573 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 N-glycosylated 1 (mouse)
mHCN1/iso:1/NGlyco:1
Yes
modification


PR:000000935 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 glycosylated form
HCN1/iso:1/GlycoRes+

modification


PR:000000984 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 N-glycosylated 1
HCN1/iso:1/NGlyco:1

organism-modification


PR:000036573 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 N-glycosylated 1 (mouse)
mHCN1/iso:1/NGlyco:1
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036573 mHCN1/iso:1/NGlyco:1
UniProtKB:O88704-1, Asn-327, MOD:00160		 located_inGO:0009986 cell surface PMID:12928435
PR:O88704-1 mHCN1/iso:1 acts_upstream_of_or_withinGO:0006812 monoatomic cation transport PMID:9630217
enablescontributes_to GO:0005222 intracellularly cAMP-activated cation channel activity PMID:11459060; PMID:9630217
GO:0005261 monoatomic cation channel activity PMID:9630217
GO:0022843 voltage-gated monoatomic cation channel activity PMID:9634236
located_inGO:0009986 cell surface PMID:15564593
GO:0030424 axon PMID:15479642
GO:0032991 protein-containing complex PMID:12034718