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Protein Ontology report - smad2 isoform Long unphosphorylated 1 (human)
PR:000045371 -
    Complex  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO namesmad2 isoform Long unphosphorylated 1 (human) 
PRO-Short-label: EXACT:hSMAD2/iso:Long/UnPhos:1
PRO-proteoform-std: EXACT:UniProtKB:Q15796-1, Ser-465/Ser-467, PR:000026291
  Definition"A mothers against decapentaplegic homolog 2 isoform Long (human) that lacks phosphorylation on the two last Ser of the C-terminal SSxS motif in human. UniProtKB:Q15796-1, Ser-465/Ser-467, PR:000026291." [PRO:CNA] 
  PRO Categoryorganism-modification 
  ParentPR:Q15796 mothers against decapentaplegic homolog 2 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Term Hierarchy
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hSMAD2/iso:Long/UnPhos:1 forms found in complexes   

hSMAD2/iso:Long/UnPhos:1 Component
PR:000045371 hSMAD2/iso:Long/UnPhos:1 PR:000025952 smad2-smad4-ski protein complex 2 (human)
PR:000025965 TGF-beta 1:type II receptor:Phospho-type I receptor:SARA:SMAD2 complex (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000045371 hSMAD2/iso:Long/UnPhos:1
UniProtKB:Q15796-1, Ser-465/Ser-467, PR:000026291
acts_upstream_of_or_withinGO:0007179 transforming growth factor beta receptor signaling pathway PMID:8752209
enablesGO:0005515 protein binding PMID:8980228
located_inGO:0005737 cytoplasm PMID:15280432; PMID:17074053
GO:0005769 early endosome PMID:12356868