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Protein Ontology report - beclin-1 (human)
PR:Q14457 - http://purl.obolibrary.org/obo/PR_Q14457
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:Q14457   
  PRO namebeclin-1 (human) 
  Synonyms
PRO-Short-label: EXACT:hBECN1
Gene-based: RELATED:BECN1 | GT197
Other: EXACT:coiled-coil myosin-like BCL2-interacting protein (human) | protein GT197 (human)
  Definition"A beclin-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q14457] 
  PRO Categoryorganism-gene 
  ParentPR:000004719 beclin-1
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:1034 BECN1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 8                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q14457
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:Q14457 beclin-1 (human)
hBECN1

organism-sequence


PR:Q14457-1 beclin-1 isoform 1 (human)
hBECN1/iso:1

organism-modification


PR:000027471 beclin-1 isoform 1 phosphorylated 1 (human)
hBECN1/iso:1/Phos:1
Yes
organism-modification


PR:000027487 beclin-1 isoform 1 unmodified form (human)
hBECN1/iso:1/UnMod

organism-modification


PR:000045927 beclin-1 phosphorylated 1 (human)
hBECN1/Phos:1

organism-modification


PR:000046478 beclin-1 phosphorylated 2 (human)
hBECN1/Phos:2

organism-modification


PR:000046479 beclin-1 ubiquitinated form (human)
hBECN1/UbiqLys+

organism-modification


PR:000049932 beclin-1 phosphorylated 3 (human)
hBECN1/Phos:3

organism-modification


PR:000049933 beclin-1 unphosphorylated 3 (human)
hBECN1/UnPhos:3

organism-modification


PR:000084621 beclin-1 glutathionylated 1 (human)
hBECN1/SGlt:1

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000027471 hBECN1/iso:1/Phos:1
UniProtKB:Q14457-1, Thr-119, MOD:00047		 acts_upstream_of_or_withinGO:0010508 positive regulation of autophagy PMID:19180116; PMID:19395874
enablesdecreased GO:0005515 protein binding with PR:P10415 BCL2 PMID:19180116
decreased GO:0005515 protein binding with PR:Q07817-1 PMID:19180116