PRO Entry Report - PR:000000060

Protein Ontology Report - hTGFBR2/var:A355P

PR:000000060 - http://purl.obolibrary.org/obo/PR_000000060

Protein Forms Annotations

Ontology Information

PRO ID

PR:000000060 Show OBO stanza / PAF / GPI

PRO name

TGF-beta receptor type-2 sequence variant A355P (human)

Synonyms

PRO-short-label:	EXACT:	hTGFBR2/var:A355P
PRO-proteoform-std:	NARROW:	UniProtKB:P37173-1, Ala-355, CHEBI:50342
Other:	EXACT:	TGF-beta receptor type-2 sequence variant 4 (human)

Definition

A TGF-beta receptor type-2 (human) that has a Pro residue at the position equivalent to Ala-355 of the amino acid sequence represented by UniProtKB:P37173-1. Example: UniProtKB:P37173-1, Ala-355, CHEBI:50342. [PMID:15731757, PRO:CNA, PRO:DAN]

PRO Category

organism-sequence

Parent

PR:P37173 TGF-beta receptor type-2 (human)

Taxon

NCBITaxon:9606 Homo sapiens

Term Hierarchy Visualization

DAG

OLS

Cytoscape

Related Cross References
DB identifiers	UniProtKB_VAR:VAR_022353

Interactive Sequence View Select/align proteoforms across species

Protein Forms

PRO ID & Category Annotation Complex	Name	Short Label	Definition & Comment

Functional Annotation

PRO Centric View
GO Centric View

PRO Term	GO Annotation		Evidence
PR:000000060 hTGFBR2/var:A355P Ala-355, CHEBI:50342	acts_upstream_of_or_within	GO:0007179 transforming growth factor beta receptor signaling pathway	PMID:15731757
	associated_with_disease_progression	DOID:0050466 Loeys-Dietz syndrome	PMID:15731757
	located_in	GO:0016020 membrane	PMID:15731757

Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0016020 membrane	PR:000000060 hTGFBR2/var:A355P Ala-355, CHEBI:50342	PMID:15731757

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