PRO ID |
PR:000000122
Show OBO stanza
/ PAF
|
PRO name |
Rho-related small GTPase |
Synonyms |
PRO-short-label: |
EXACT: |
fam:RHO |
|
Definition |
A small GTPase with a short insert (approximately 13 residues) coincident with loop 8 of Ras. This insert region forms a highly charged helix without dramatic disturbance of the global structure shared with other small GTPases. Rho-related small GTPases act as key transducers of extracellular signals to regulate the actin cytoskeleton, cell cycle progression and gene expression.
[PMID:11463812]
|
PRO Category |
family |
Parent |
PR:000000028 small GTPase |
Term Hierarchy Visualization |
DAG
OLS
Cytoscape
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