PRO Entry Report - PR:000000168

Protein Ontology Report - BMP7

PR:000000168 - http://purl.obolibrary.org/obo/PR_000000168

Protein Forms Annotations

Ontology Information

PRO ID

PR:000000168 Show OBO stanza / PAF

PRO name

bone morphogenetic protein 7

Synonyms

PRO-short-label:	EXACT:	BMP7
Gene-based:	RELATED:	OP1
Other:	EXACT:	BMP-7 \| OP-1 \| eptotermin alfa \| osteogenic protein 1

Definition

A bone morphogenetic protein that is a translation product of the human BMP7 gene or a 1:1 ortholog thereof. [PRO:CNA]

PRO Category

gene

Parent

PR:000000034 bone morphogenetic protein

Terms by PRO Category

Retrieve All terms OBO Stanza / PAF

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
gene	1	organism-gene	2
sequence	1	organism-sequence	2
modification	6	organism-modification	4
union	0

Term Hierarchy Visualization

DAG

OLS

Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms

PRO ID & Category Annotation Complex	Name	Short Label	Definition & Comment

Functional Annotation

PRO Centric View
GO Centric View

PRO Term	GO Annotation		Evidence
PR:000036517 hBMP7/iso:1/mature/NGlyco:1 Asn-372, MOD:00160	enables	GO:0042803 protein homodimerization activity	PMID:15929982, PMID:8570652
	enables	GO:0005102 signaling receptor binding	PMID:9872992
	located_in	GO:0005615 extracellular space	PMID:15047707, PMID:15929982
PR:000036516 mBMP7/iso:1/mature	acts_upstream_of_or_within	GO:0007411 axon guidance	PMID:12741987
	enables	GO:0005515 protein binding	PMID:12741987
	located_in	GO:0005615 extracellular space	PMID:12741987
PR:P23359 mBMP7	acts_upstream_of_or_within	GO:0042475 odontogenesis of dentin-containing tooth	PMID:15525533
	acts_upstream_of_or_within	GO:0007435 salivary gland morphogenesis	PMID:11731698
	acts_upstream_of_or_within	GO:0048754 branching morphogenesis of an epithelial tube	PMID:15831470
	acts_upstream_of_or_within	GO:0009887 animal organ morphogenesis	PMID:7590254
	acts_upstream_of_or_within	GO:0035239 tube morphogenesis	PMID:15831470
PR:000036519 hBMP7/iso:1/mature/NGlyco:2 Asn-372, MOD:00160	enables	NOT GO:0005102 signaling receptor binding	PMID:15929982
PR:000036519 hBMP7/iso:1/mature/NGlyco:2 Asn-372, MOD:00160	located_in	GO:0005615 extracellular space	PMID:15929982
PR:000036518 mBMP7/iso:1/mature/NGlyco:1 Asn-371, MOD:00160	acts_upstream_of_or_within	GO:0030509 BMP signaling pathway	PMID:14623234
PR:P18075-1 hBMP7/iso:1	acts_upstream_of_or_within	GO:0001501 skeletal system development	PMID:2357959
	enables	GO:0005515 protein binding	PMID:12805376
	located_in	GO:0005794 Golgi apparatus	PMID:12805376
PR:P23359-1 mBMP7/iso:1	acts_upstream_of_or_within	GO:0030509 BMP signaling pathway	PMID:14623234

Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0005794 Golgi apparatus	PR:P18075-1 hBMP7/iso:1	PMID:12805376
GO:0005615 extracellular space	PR:000036516 mBMP7/iso:1/mature	PMID:12741987
	PR:000036517 hBMP7/iso:1/mature/NGlyco:1 Asn-372, MOD:00160	PMID:15047707, PMID:15929982
	PR:000036519 hBMP7/iso:1/mature/NGlyco:2 Asn-372, MOD:00160	PMID:15929982

top