PRO Entry Report - PR:000000375

Protein Forms Annotations

Ontology Information

PRO ID

PR:000000375 Show OBO stanza / PAF

PRO name

smad9

Synonyms

PRO-short-label:	EXACT:	SMAD9
Gene-based:	RELATED:	MADH6 \| MADH9 \| Madh8 \| SMAD8
Other:	EXACT:	MAD homolog 9 \| Madh6 \| SMAD 9 \| SMAD family member 9 \| mothers against DPP homolog 9 \| smad8

Definition

A BMP receptor-regulated smad protein that is a translation product of the human SMAD9 gene or a 1:1 ortholog thereof. [PMID:10708948]

PRO Category

gene

Parent

PR:000000038 BMP receptor-regulated smad protein

Terms by PRO Category

Retrieve All terms OBO Stanza / PAF

Term Hierarchy Visualization

DAG

OLS

Interactive Sequence View Select/align proteoforms across species

Protein Forms

PRO ID & Category Annotation Complex	Name	Short Label	Definition & Comment

Functional Annotation

PRO Term	GO Annotation		Evidence
PR:Q9JIW5-1 mSMAD9/iso:1	acts_upstream_of_or_within	GO:0048856 anatomical structure development	PMID:15899870
PR:Q9JIW5-1 mSMAD9/iso:1	located_in	GO:0005622 intracellular anatomical structure	PMID:10814522
PR:000029959 hSMAD9/iso:3	acts_upstream_of_or_within	GO:0030514 negative regulation of BMP signaling pathway	PMID:10583507
	enables	GO:0046332 SMAD binding	PMID:10583507
	located_in	GO:0005737 cytoplasm	PMID:10583507
PR:000036567 mSMAD9/iso:1/Phos:1 Ser-428/Ser-430, MOD:00046	acts_upstream_of_or_within	GO:0030509 BMP signaling pathway	PMID:11163184, PMID:15542835
	enables	GO:0005515 protein binding	PMID:11163184, PMID:15542835
	located_in	GO:0005634 nucleus	PMID:10814522

Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0005634 nucleus	PR:000036567 mSMAD9/iso:1/Phos:1 Ser-428/Ser-430, MOD:00046	PMID:10814522
GO:0005737 cytoplasm	PR:000029959 hSMAD9/iso:3	PMID:10583507
GO:0005622 intracellular anatomical structure	PR:Q9JIW5-1 mSMAD9/iso:1	PMID:10814522

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