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Protein Ontology Report - KCNN3

PR:000000714 -
Ontology Information
PRO ID PR:000000714 Show OBO stanza / PAF
PRO name small conductance calcium-activated potassium channel protein 3
PRO-short-label: EXACT: KCNN3
Gene-based: RELATED: K3
Other: EXACT: KCa2.3 | SK3 | SKCa 3 | SKCa3
Definition A calcium-activated calmodulin-binding potassium channel alpha subunit that is a translation product of the human KCNN3 gene or a 1:1 ortholog thereof. The KCNN3 gene contains two arrays of CAG trinucleotide repeats, which are highly polymorphic. The SK3 channels are thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. [PRO:CNA]
PRO Category gene
Parent PR:000000668 calcium-activated calmodulin-binding potassium channel alpha subunit
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 1 organism-sequence 4
modification 0 organism-modification 0
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
enables NOT GO:0015269 calcium-activated potassium channel activity PMID:11395478
located_in GO:0005634 nucleus PMID:11395478
located_in GO:0009986 cell surface PMID:11395478
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:000029956 hKCNN3/var:1

GO:0009986 cell surface PR:Q9UGI6-1 hKCNN3/iso:1