PRO ID |
PR:000001659
Show OBO stanza
/ PAF
|
PRO name |
prostaglandin E2 receptor EP3 subtype |
Synonyms |
PRO-short-label: |
EXACT: |
PTGER3 |
Gene-based: |
RELATED: |
Ptgerep3 |
Other: |
EXACT: |
PGE receptor EP3 subtype | PGE2 receptor EP3 subtype | PGE2-R | prostaglandin E2 receptor EP3 | prostanoid EP3 receptor |
|
Definition |
A prostanoid receptor that is a translation product of the human PTGER3 gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin E2 (PGE2). This receptor is the most ubiquitous of the prostaglandin E2 receptors, mediating contraction of gastrointestinal, uterine, and vascular smooth muscle, inhibition of neurotransmitter release from autonomic nerves, inhibition of lipolysis in adipocytes, inhibition of acid secretion from gastric mucosa, and inhibition of water reabsorption in kidney.
[PMID:7938166, PRO:WCB]
|
PRO Category |
gene |
Parent |
PR:000001549 prostanoid receptor |
Terms by PRO Category |
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/ PAF
Organism-Independent |
Organism-Specific |
Category |
Number of Terms |
Category |
Number of Terms |
gene
|
1 |
organism-gene
|
3 |
sequence
|
3 |
organism-sequence
|
18 |
modification
|
0 |
organism-modification
|
0 |
union
|
0 |
|
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