Protein Ontology Report - TANK PR:000003146 - http://purl.obolibrary.org/obo/PR_000003146

Ontology Information
PRO ID	PR:000003146 Show OBO stanza / PAF
PRO name	TRAF family member-associated NF-kappa-B activator
Synonyms	PRO-short-label: EXACT: TANK Gene-based: RELATED: ITRAF | TRAF2 Other: EXACT: I-TRAF BROAD: TRAF-interacting protein
Definition	A protein that is a translation product of the human TANK gene or a 1:1 ortholog thereof. [PRO:CNA]
PRO Category	gene
Parent	PR:000000001 protein
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Independent Organism-Specific Category Number of Terms Category Number of Terms gene 1 organism-gene 2 sequence 1 organism-sequence 7 modification 3 organism-modification 2 union 0
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All gene organism-gene sequence organism-sequence modification organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

TANK forms found in complexes

TANK Component Complexes PR:000036091 mTANK/iso:1/K63polyUbiq+ PR:000036095 K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex (mouse) PR:000036091 mTANK/iso:1/K63polyUbiq+ PR:000036093 tbk1:K63-poly-Ub-tank:Ikke:traf3:ticam1:ticam2:activated TLR4 complex (mouse) PR:000036091 mTANK/iso:1/K63polyUbiq+ PR:000036097 tbk1:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex (mouse) PR:000036091 mTANK/iso:1/K63polyUbiq+ PR:000036099 ikke:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex (mouse) PR:P70347 mTANK PR:000036090 tbk1:tank:ikke:traf3:ticam1:ticam2:activated TLR4 complex (mouse) PR:P70347 mTANK PR:000036149 tbk1:tank:ikke complex (mouse) PR:P70347 mTANK PR:000037313 tbk1:tank:ikke:traf3:ticam1:activated TLR3 complex (mouse)

Functional Annotation PRO Centric View GO Centric View
PRO Term GO Annotation Evidence PR:000036149 tbk1:tank:ikke complex (mouse) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway PMID:17823124 PR:000037313 tbk1:tank:ikke:traf3:ticam1:activated TLR3 complex (mouse) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway PMID:12133833, PMID:17327220

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