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Protein Ontology Report - SKI

PR:000003214 - http://purl.obolibrary.org/obo/PR_000003214
Ontology Information
PRO ID PR:000003214 Show OBO stanza / PAF
PRO name ski oncogene
Synonyms
PRO-short-label: EXACT: SKI
Other: EXACT: proto-oncogene c-Ski
Definition A protein that is a translation product of the human SKI gene or a 1:1 ortholog thereof. [PRO:CNA]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 1 organism-sequence 2
modification 0 organism-modification 0
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

SKI forms found in complexes
SKI Component Complexes
PR:000025948 SKI/iso:1 PR:000025972 smad2-smad4-ski protein complex 2
PR:000025948 SKI/iso:1 PR:000025971 smad2-smad4-ski protein complex 1
PR:P12755-1 hSKI/iso:1 PR:000025952 smad2-smad4-ski protein complex 2 (human)
PR:P12755-1 hSKI/iso:1 PR:000025951 smad2-smad4-ski protein complex 1 (human)

Functional Annotation
PRO Term GO Annotation Evidence
PR:000025952
smad2-smad4-ski protein complex 2 (human)
acts_upstream_of_or_within GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway PMID:12732634
located_in GO:0005737 cytoplasm PMID:12732634
PR:000025951
smad2-smad4-ski protein complex 1 (human)
acts_upstream_of_or_within GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway PMID:10485843
located_in GO:0005634 nucleus PMID:10485843
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:000025951 smad2-smad4-ski protein complex 1 (human)

PMID:10485843
GO:0005737 cytoplasm PR:000025952 smad2-smad4-ski protein complex 2 (human)

PMID:12732634

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