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Protein Ontology Report - smad2-smad4-ski protein complex 1 (human)

PR:000025951 -
Ontology Information
PRO ID PR:000025951 Show OBO stanza / PAF / GPI
PRO name smad2-smad4-ski protein complex 1 (human)
Definition A smad2-smad4-ski protein complex 1 with phosphorylated smad2 in human. [PRO:CNA]
PRO Category organism-complex
Parent PR:000025971 smad2-smad4-ski protein complex 1
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Category Number of Terms
organism-complex 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000025951 PR:P12755-1 ski oncogene isoform 1 (human) hSKI/iso:1 A ski oncogene isoform 1 that is encoded in the genome of human. [PMID:2762147, PRO:CNA]
PR:Q13485-1 mothers against decapentaplegic homolog 4 isoform 1 (human) hSMAD4/iso:1 A smad4 isoform 1 that is encoded in the genome of human. [PRO:CNA]
PR:000025934 smad2 isoform Long phosphorylated 1 (human) hSMAD2/iso:Long/Phos:1 A smad2 isoform Long phosphorylated 1 in human. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q15796-1, Ser-465/Ser-467, MOD:00046. [PMID:8980228, PMID:9346966]

Functional Annotation
PRO Term GO Annotation Evidence
smad2-smad4-ski protein complex 1 (human)
acts_upstream_of_or_within GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway PMID:10485843
located_in GO:0005634 nucleus PMID:10485843
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:000025951 smad2-smad4-ski protein complex 1 (human)