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Protein Ontology Report - h(pSMAD2:SMAD4):1

PR:000025933 -
Ontology Information
PRO ID PR:000025933 Show OBO stanza / PAF / GPI
PRO name smad2-smad4 protein complex 1 (human)
PRO-short-label: EXACT: h(pSMAD2:SMAD4):1
Definition A smad2-smad4 protein complex 1 whose components are encoded in the genome of human. [PRO:CNA]
PRO Category organism-complex
Parent PR:000025967 smad2-smad4 protein complex 1
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Category Number of Terms
organism-complex 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000025933 PR:Q13485 mothers against decapentaplegic homolog 4 (human) hSMAD4 A smad4 that is encoded in the genome of human. [PRO:CNA, UniProtKB:Q13485] 1
PR:000025934 smad2 isoform Long phosphorylated 1 (human) hSMAD2/iso:Long/Phos:1 A smad2 isoform Long phosphorylated 1 in human. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q15796-1, Ser-465/Ser-467, MOD:00046. [PMID:8980228, PMID:9346966] 2

Functional Annotation
PRO Term GO Annotation Evidence
smad2-smad4 protein complex 1 (human)
acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:8752209, PMID:8980228
located_in GO:0005829 cytosol Reactome:REACT_7344
located_in GO:0005654 nucleoplasm Reactome:REACT_7382
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005829 cytosol PR:000025933 smad2-smad4 protein complex 1 (human)

GO:0005654 nucleoplasm PR:000025933 smad2-smad4 protein complex 1 (human)