A protein-containing complex that is heterodimeric consisting of one subunit of serine palmitoyltransferase 1 and serine palmitoyltransferase 3. These components are encoded in the genome of human. The biological unit of SPT complex may consist of multiple copies of the core 1 and/or core 2 in combination with additional subunits.
[PMID:17331073, PMID:19648650, PRO:CNA]
This entity is disposed to have the enzymatic activity described by EC:220.127.116.11.