Protein Ontology Report - serine palmitoyltransferase complex 5 (human) PR:000026153 - http://purl.obolibrary.org/obo/PR_000026153

Ontology Information
PRO ID	PR:000026153 Show OBO stanza / PAF / GPI
PRO name	serine palmitoyltransferase complex 5 (human)
Definition	A serine palmitoyltransferase complex whose components are the same as serine palmitoyltransferase complex core 1 (serine palmitoyltransferase 1 and serine palmitoyltransferase 2) plus the accessory small subunit A. These components are encoded in the genome of human. The biological unit of SPT complex may consist of multiple copies of the core 1 and/or core 2 in combination with additional subunits. [PMID:17331073, PMID:19648650, PRO:CNA]
Comment	This entity is disposed to have the enzymatic activity described by EC:2.3.1.50.
PRO Category	organism-complex
Parent	GO:0017059 serine C-palmitoyltransferase complex
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-complex 1
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Complex Forms Display Category: All All organism-complex
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits

Complex PRO ID Name Short Label Definition Number in Complex PR:000026153 PR:Q969W0 serine palmitoyltransferase small subunit A (human) hSPTSSA A serine palmitoyltransferase small subunit A that is encoded in the genome of human. [PMID:19416851, PRO:CNA] PR:O15270 serine palmitoyltransferase 2 (human) hSPTLC2 A serine palmitoyltransferase 2 that is encoded in the genome of human. [PRO:CNA] PR:O15269 serine palmitoyltransferase 1 (human) hSPTLC1 A serine palmitoyltransferase 1 that is encoded in the genome of human. [PRO:CNA]

Functional Annotation PRO Centric View GO Centric View
PRO Term GO Annotation Evidence PR:000026153 serine palmitoyltransferase complex 5 (human) enables GO:0004758 serine C-palmitoyltransferase activity increased relative to PR:000026144 serine palmitoyltransferase complex core 1 (human) PMID:19416851

top