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Protein Ontology Report - serine palmitoyltransferase complex 6 (human)

PR:000026154 - http://purl.obolibrary.org/obo/PR_000026154
Ontology Information
PRO ID PR:000026154 Show OBO stanza / PAF
PRO name serine palmitoyltransferase complex 6 (human)
Definition A serine palmitoyltransferase complex whose components are the same as serine palmitoyltransferase complex core 1 (serine palmitoyltransferase 1 and serine palmitoyltransferase 2) plus the accessory small subunit B. These components are encoded in the genome of human. The biological unit may consist of multiple copies of the core 1 and/or core 2 in combination with additional subunits. [PMID:17331073, PMID:19648650, PRO:CNA]
Comment This entity is disposed to have the enzymatic activity described by EC:2.3.1.50.
PRO Category organism-complex
Parent GO:0017059 serine C-palmitoyltransferase complex
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-complex 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000026154 PR:Q8NFR3 serine palmitoyltransferase small subunit B (human) hSPTSSB A serine palmitoyltransferase small subunit B that is encoded in the genome of human. [PMID:19416851, PRO:CNA]
PR:O15270 serine palmitoyltransferase 2 (human) hSPTLC2 A serine palmitoyltransferase 2 that is encoded in the genome of human. [PRO:CNA]
PR:O15269 serine palmitoyltransferase 1 (human) hSPTLC1 A serine palmitoyltransferase 1 that is encoded in the genome of human. [PRO:CNA]


Functional Annotation
PRO Term GO Annotation Evidence
PR:000026154
serine palmitoyltransferase complex 6 (human)
enables GO:0004758 serine C-palmitoyltransferase activity increased relative to PR:000026144 serine palmitoyltransferase complex core 1 (human) PMID:19416851

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