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Protein Ontology Report - (pIRF3:pIRF7)

PR:000027083 -
Ontology Information
PRO ID PR:000027083 Show OBO stanza
PRO name IRF3-P:IRF7-P complex
PRO-short-label: EXACT: (pIRF3:pIRF7)
Other: EXACT: IRF3pIRF7p
Definition A protein-containing complex that is composed of a heterodimer of phosphorylated IRF-3 and phosphorylated IRF-7. [PMID:18068231, PRO:CNA, TLR:AMM]
Comment Requested by=TLR.
PRO Category complex
Parent GO:0032991 protein-containing complex
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
complex 1 organism-complex 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000027084 PR:000027082 interferon regulatory factor 7 isoform 1 phosphorylated 1 (human) hIRF7/iso:1/Phos:1 An interferon regulatory factor 7 isoform 1 phosphorylated 1 in human. UniProtKB:Q92985-1, Ser-477/Ser-479, MOD:00046. [PMID:10893229, PMID:14517278, TLR:AMM] 1
PR:000045489 interferon regulatory factor 3 isoform 1 phosphorylated 2 (human) hIRF3/iso:1/Phos:2 An interferon regulatory factor 3 isoform 1 (human) that has been phosphorylated in Ser-339 and Ser and Thr residues within the two phosphorylation cluster sites. A Ser-386 on the 2S site and multiple Ser and Thr residues in the 5ST site (Ser-396, Ser-498, Ser-402, Thr-404, and Ser-405). UniProtKB:Q14653-1, Ser-339/Ser-386/Ser-398/Ser-402/Ser-405, MOD:00046|Thr-404, MOD:00047. [PRO:CNA, Reactome:R-HSA-936418] 1